The timing of complementary feeding in preterm infants and the effect on overweight: study protocol for a systematic review
The timing of complementary feeding in preterm infants and the effect on overweight: study protocol for a systematic review
复制标题
早产儿补充喂养的时机及其对超重的影响：系统评价的研究方案
作者：
K. Vissers;E. Feskens;J. V. van Goudoever;A. Janse
背景在足月儿中，有证据表明早期补充喂养是儿童肥胖的危险因素。因此，在婴儿期及时引入补充喂养是必要的。世界卫生组织(WHO)和欧洲儿科胃肠病学、肝病和营养学会(ESPGHAN)都提出了开始对足月儿进行补充喂养的建议。然而，这些指南不能直接翻译成早产儿。最近的文献对早产儿引入补充喂养提供了对比信息。鉴于这些关于在早产儿中引入固体食品的不同报告，有必要进行系统的审查。本研究的主要目的是分析开始补充喂养的时间对早产儿超重(包括肥胖)的影响。方法利用Cochrane、PubMed、EMBASE、Web of Science、Scope us和CINAHL进行电子系统文献检索。不会有时间限制。首先，来自随机对照试验(RCT)的数据将包括在这项系统性综述中。搜索词将包括早产儿、补充喂养、超重及其同义词。文章选择，包括偏差风险评估，将由三名评审员独立进行。体重指数标准差得分(BMI-SDS或BMI-Z得分)将用于比较研究。所有研究结果的一致性将影响是否将结果合并到荟萃分析中的决定。不能纳入Meta分析的研究将在叙述性分析中描述。讨论这一系统综述将概述关于早产儿补充喂养的时机和对超重的影响的现有知识。它将成为未来早产儿补充喂养指南的基础。系统审查注册PROSPERO CRD42015014215
BackgroundIn term infants, there is evidence that early complementary feeding is a risk factor for childhood obesity. Therefore, timely introduction of complementary feeding during infancy is necessary. The World Health Organization (WHO) and European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) both developed recommendations for the start of complementary feeding for term-born infants. However, these guidelines cannot be directly translated to preterm infants. Recent literature looking at the introduction of complementary feeding in preterm infants gives contrasting information. Given these contrasting reports on the introduction of solid foods in premature born infants, a systematic review is needed. The primary objective of this study is to analyze the effect of the time starting complementary feeding on overweight (including obesity) in preterm infants.MethodsAn electronic systematic literature search with pre-defined terms will be conducted in Cochrane, PubMed, EMBASE, Web of Science, Scopus, and CINAHL. There will be no restriction for time period. Primarily, data from randomized controlled trials (RCTs) will be included in this systematic review. Search terms will include preterm infants, complementary feeding, overweight, and their synonyms. Article selection, including risk of bias assessment, will be performed by three reviewers independently. Body mass index standard deviation score (BMI-SDS or BMI-Z-score) will be used to compare studies. The consistency of results across the studies will influence the decision whether or not to combine results in a meta-analysis. Studies that cannot be included in the meta-analysis will be described in a narrative analysis.DiscussionThis systematic review will give an overview of the existing knowledge on the timing of complementary feeding in preterm infants and the effect on overweight. It will form a basis for future guidelines for complementary feeding for preterm infants.Systematic review registrationPROSPERO CRD42015014215
DOI：
10.1016/j.jpeds.2013.06.032
发表时间：
2013-12
期刊：
The Journal of pediatrics
影响因子：
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作者：
Belfort MB;Gillman MW;Buka SL;Casey PH;McCormick MC
通讯作者：
McCormick MC