Periodontal status of individuals in early stages of human immunodeficiency virus infection.
Periodontal status of individuals in early stages of human immunodeficiency virus infection.
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人类免疫缺陷病毒感染早期个体的牙周状况。
DOI：
10.1111/j.1600-0528.1991.tb00168.x
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发表时间：
1991
影响因子：
2.3
通讯作者：
Volberding,PA
中科院分区：
文献类型：
--
作者：
Drinkard,CR;Decher,L;Little,JW;Rhame,FS;BalfourJr,HH;Rhodus,NL;Merry,JW;Walker,PO;Miller,CE;Volberding,PA
本研究的目的是评估牙周健康和人类免疫缺陷病毒感染之间的关联在疾病的早期阶段的个人谁参加随机安慰剂对照临床试验齐多夫定。以前的报告描述了一个快速进行性牙周炎和非典型牙龈炎与晚期感染的人类免疫缺陷病毒。每例受试者填写健康史。在97例无症状患者和9例艾滋病相关综合征（ARC）患者的常规门诊访视期间完成了基线口腔检查。在整个48周口服研究期间，每隔3个月进行一次随访检查。对菌斑、牙石、牙龈异常、龋齿和牙周病进行了评价。牙周炎的测量包括菌斑指数（PI），牙龈指数（GI），出血指数（BI），探诊深度（PD），并观察每例患者的6颗牙齿上的弹坑，坏死和牙齿移动。超过一半的受试者在前一年看过牙医，并进行了口腔预防;其中不到25%的人进行了修复工作或拔牙。在研究过程中，无症状和ARC的牙周指数平均值分别为：PI：0.9（SE 0.04）和0.9（SE 0.08），P = 0.818; GI：1.0（SF. 0.04）和0.9（SF 0.07），p= 0.412; BI：0.6（SE 0.04）和0.4（SF 0.07），p= 0.278; PD：2.9（SE 0.05）和2.6（SE 0.10），p= 0.140。两组中均未发现弹坑、坏死或牙齿松动的证据。很少有牙石或龋齿。ARC与无症状患者之间未检测到临床显著差异。牙科病史和口腔检查显示，两组HIV疾病早期患者的牙周健康状况良好。
The purpose of this study was to evaluate the association of periodontal health and human immunodeficiency virus infection among individuals in the early stages of disease who were participating in randomized placebo‐controlled clinical trials of zidovudine. Previous reports have described a rapidly progressive periodontitis and atypical gingivitis associated with late stages of infection by the human immunodeficiency virus. A health history was completed by each subject. Baseline oral examinations were completed on 97 asymptomatic patients and nine with AIDS‐related complex (ARC) during their regular clinic visit. Follow‐up examinations were conducted at 3‐month intervals throughout the 48 weeks of the oral study. Evaluations of plaque, calculus, gingival abnormalities, caries, and periodontal disease were conducted. Periodontal measurements included plaque index (PI), gingival index (GI), bleeding index (BI), probing depth (PD), and observation for cratering, necrosis, and tooth mobility on six teeth in each patient. More than half of the subjects had visited their dentist during the previous year and had had an oral prophylaxis; less than 25% of them had had either restorative work or extractions. The mean scores for periodontal indices averaged over the course of the study in asymptomatic and ARC respectively were: PI: 0.9 (SE 0.04) and 0.9 (SE 0.08), P = 0.818; GI: 1.0 (SF. 0.04) and 0.9 (SF 0.07).p= 0.412; BI: 0.6 (SE 0.04) and 0.4 (SF 0.07).p= 0.278; PD: 2.9 (SE 0.05) and 2.6 (SE 0.10).p= 0.140. There was no evidence of cratering, necrosis, or tooth mobility in either group. Few had calculus or dental caries. There were no clinically significant differences detected between ARC versus asymptomatic patients. Dental histories and oral examinations showed that two groups of patients in early stages of HIV‐disease were in good periodontal health.
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口腔粘膜病变：与人类免疫缺陷病毒抗体的存在有关。
DOI：
10.1016/0030-4220(89)90112-6
发表时间：
1989
期刊：
Oral surgery, oral medicine, and oral pathology
影响因子：
--
作者：
Melnick,SL;Engel,D;Truelove,E;DeRouen,T;Morton,T;Schubert,M;Dunphy,C;Wood,RW
通讯作者：
Wood,RW
与 HIV 感染相关的口腔病变的分类。
DOI：
--
发表时间：
1989
期刊：
Oral surgery, oral medicine, and oral pathology
影响因子：
--
作者：
J. Pindborg
通讯作者：
J. Pindborg
艾滋病患者或艾滋病高危人群的口腔发现：对 375 名同性恋男性的研究。
DOI：
--
发表时间：
1986
期刊：
The Journal of the American Dental Association (1939)
影响因子：
--
作者：
S. Silverman;C. Migliorati;F. Lozada‐Nur;D. Greenspan;M. Conant
通讯作者：
M. Conant
影响因子：
39.2
作者：
FISCHL, MA;RICHMAN, DD;ANDERSON, J
通讯作者：
ANDERSON, J
DOI：
--
发表时间：
1987
期刊：
The Journal of Periodontology
影响因子：
--
作者：
B. Pihlstrom;Larry F. Wolff;M. Bashar Bakdash;Erwin M. Schaffer;James R. Jensen;Dorothee M. Aeppli;C. Bandt
通讯作者：
C. Bandt