Post-traumatic stress disorder: facts and fiction
Post-traumatic stress disorder: facts and fiction
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创伤后应激障碍：事实与虚构
DOI：
10.1097/yco.0b013e3282f269ee
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发表时间：
2008
影响因子：
6.9
通讯作者：
L. Fostick
中科院分区：
文献类型：
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作者：
J. Zohar;A. Juven;Vicki Myers;L. Fostick
回顾的目的这篇综述提供了当代对创伤后应激障碍的最新观点，并挑战了有关该疾病及其治疗的神话。由于国际恐怖主义的影响，创伤后应激障碍最近引起了公众的注意，尽管绝大多数创伤后应激障碍病例实际上与车祸、强奸和暴力抢劫等平民事件有关。这种疾病需要专业人士更深入的理解和共识。最近的发现在阐明这种疾病的神经生物学方面取得了进展，部分是通过使用创伤后应激障碍的动物模型。最近的研究集中在记忆过程和下丘脑-垂体-肾上腺轴的可塑性所发挥的治疗作用，以及这如何适合（或不适合）与当前的治疗干预。各机构已经制定了指导方针，试图简化治疗方案。对创伤后应激障碍的理解是不完整的。未来的研究应该试图确定在“机会之窗”（从暴露到创伤后应激障碍发展的时间）期间给予的治疗是有效的。应注意不要干扰自发恢复。
Purpose of review This review provides an update on contemporary perspectives on post-traumatic stress disorder and challenges myths about the disorder and its treatment. Post-traumatic stress disorder has recently attracted public attention because of the impact of international terrorism, although the vast majority of post-traumatic stress disorder cases actually relate to civilian events such as car accidents, rape and violent robbery. This disorder requires deeper understanding and consensus among professionals. Recent findings Advances have been made in elucidating the neurobiology of this disorder, partly by using an animal model of post-traumatic stress disorder. Recent studies have focused on memory processes and the therapeutic role played by plasticity of the hypothalamic–pituitary–adrenal axis, and how this fits (or does not fit) in with the current therapeutic interventions. Guidelines have been established by various bodies in an attempt to streamline treatment options. Summary Understanding of post-traumatic stress disorder is incomplete. Future research should attempt to determine what treatments given during the ‘window of opportunity’ – the time from exposure until post-traumatic stress disorder develops – are effective. Care should be taken not to interfere with spontaneous recovery.
影响因子：
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作者：
KESSLER, RC;SONNEGA, A;NELSON, CB
通讯作者：
NELSON, CB