Molecular physiology of olfaction.

Molecular physiology of olfaction.
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嗅觉的分子生理学。

DOI:
10.1152/ajpcell.1989.257.6.c1043
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发表时间:
1989
期刊:
The American journal of physiology
影响因子:
--
通讯作者:
Anholt,RR
Anholt,RR
中科院分区:
--
文献类型:
--
作者:
Anholt,RR

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嗅觉接受是由位于嗅上皮中的嗅觉受体细胞介导的。这些细胞是双极神经元,它们向鼻腔延伸树枝状突起,并向大脑中的嗅球延伸轴突。树突具有一组顶端纤毛,包埋在粘液中。气味识别和信号转导起始于这些化学感受纤毛的膜,并在嗅觉受体细胞的兴奋中达到高潮。嗅觉受体细胞的不同群体的气味剂的差异激活产生编码气味质量和浓度的神经元活动的模式。初级气味识别位点在睫状膜的身份仍有待建立。然而,一个显着的身体的信息已经成为关于嗅觉转导机制。现在越来越清楚的是,嗅觉转导涉及到几个第二信使系统的相互作用,以控制这些敏感的化学感受神经元的反应。
Olfactory reception is mediated by olfactory receptor cells located in the olfactory epithelium. These cells are bipolar neurons that extend a dendrite toward the nasal lumen and an axon toward the olfactory bulb in the brain. The dendrite possesses a group of apical cilia embedded in mucus. Odorant recognition and signal transduction are initiated at the membranes of these chemosensory cilia and culminate in excitation of the olfactory receptor cell. Differential activation by odorants of distinct groups of olfactory receptor cells generates patterns of neuronal activity that encode odor quality and concentration. The identities of primary odorant recognition sites at the ciliary membrane remain to be established. However, a significant body of information has become available with respect to olfactory transduction mechanisms. It is now becoming clear that olfactory transduction involves the interplay of several second messenger systems to control the responses of these exquisitely sensitive chemosensory neurons.
对安全问题的回应
DOI: --
发表时间: 1988
期刊:
影响因子: --
作者:
P. Aysola;Perry Anderson;C. Langford
通讯作者: C. Langford
与在微波能量加热的压力下湿灰化样品相关的安全问题
DOI: --
发表时间: 1988
期刊:
影响因子: --
作者:
L. Gilman;Will. Grooms
通讯作者: Will. Grooms
使用聚四氟乙烯容器在微波炉中在压力下对生物样品进行湿灰化。
DOI: --
发表时间: 1987
影响因子: 7.4
作者:
P. Aysola;P. Anderson;C. Langford
通讯作者: C. Langford
DOI: 10.1021/ac00125a038
发表时间: 1986-10-01
影响因子: 7.4
作者:
KINGSTON, HM;JASSIE, LB
通讯作者: JASSIE, LB