From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?
From ARDS to pulmonary fibrosis: the next phase of the COVID-19 pandemic?
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DOI:
10.1016/j.trsl.2021.09.001
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发表时间:
2022-03
期刊:
影响因子:
--
通讯作者:
Schwartz DA
中科院分区:
文献类型:
--
作者:
Michalski JE;Kurche JS;Schwartz DA
While the coronavirus disease 19 (COVID-19) pandemic has transformed the medical and scientific communites since it was first reported in late 2019, we are only beginning to understand the chronic health burdens associated with this disease. Although COVID-19 is a multi-systemic disease, the lungs are the primary source of infection and injury, resulting in pneumonia and, in severe cases, acute respiratory distress syndrome (ARDS). Given that pulmonary fibrosis is a well-recognized sequela of ARDS, many have questioned whether COVID-19 survivors will face long-term pulmonary consequences. This review is aimed at integrating our understanding of the pathophysiologic mechanisms underlying fibroproliferative ARDS with our current knowledge of the pulmonary consequences of COVID-19 disease.
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DOI:
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发表时间:
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期刊:
The European respiratory journal
影响因子:
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