Assessing young Kenyan women's willingness to engage in a peer-delivered HIV self-testing and referral model for PrEP initiation: A qualitative formative research study.
Assessing young Kenyan women's willingness to engage in a peer-delivered HIV self-testing and referral model for PrEP initiation: A qualitative formative research study.
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DOI：
10.3389/fpubh.2022.932948
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发表时间：
2022
影响因子：
5.2
通讯作者：
Roche, Stephanie D. D.
中科院分区：
文献类型：
--
作者：
McGowan, Maureen;Casmir, Edinah;Wairimu, Njeri;Mogere, Peter;Jahn, Albrecht;Ngure, Kenneth;Ortblad, Katrina F. F.;Roche, Stephanie D. D.
暴露前预防（PrEP）对于预防艾滋病毒非常有效，但接受率仍然很低，特别是在肯尼亚的青春期女孩和年轻女性（AGYW）中。一个模型，其中受过训练的AGYW使用PrEP提供艾滋病毒自我测试给他们的亲密朋友，并将他们转介到PrEP可能有助于增加该人群的PrEP吸收。为了了解AGYW参与这种模式的潜在意愿，我们在肯尼亚进行了一项定性的形成性研究。我们在基安布县对被确定有艾滋病毒感染风险的AGYW（16至24岁）进行了半结构化深入访谈（IDIs）。我们有目的地招募了“PrEP-naïve”（以前没有使用PrEP）和“PrEP-experienced”AGYW，他们在过去一年中使用了PrEP至少1个月。我们征求了关于发起/参与有关艾滋病毒风险和PrEP的对话，分发/接收艾滋病毒自我检测试剂盒以及转介/跟进诊所艾滋病毒服务的观点。我们分析逐字记录使用快速定性分析和归纳和演绎的方法相结合，后者由综合行为模型（IBM）通知。从2020年8月至12月，我们进行了30次IDI：15次使用PrEP经验丰富的AGYW，15次使用PrEP初治的AGYW。参与者的中位年龄为20岁[四分位距（IQR）：20-22]。总体而言，大多数参与者预计他们愿意参与这一模式。有PrEP经验的AGYW强调了他们对朋友艾滋病毒风险行为的关注，其中一些人指出他们已经习惯与朋友讨论PrEP。此外，许多人对拟议的目标行为表示积极的态度，认为这些行为在AGYW中是规范的，并表示相信他们有能力在适当的支持下实施这些行为。虽然很少有参与者有艾滋病毒的经验，几乎所有的预期，他们将能够正确使用艾滋病毒自我检测试剂盒，如果提供的指导。参与本研究的肯尼亚AGYW普遍预计，他们愿意参与正式的同侪PrEP转介模式，并通过同侪提供的艾滋病毒自我检测来增强。未来的研究需要对该模型进行试点测试，以确定其可接受性，可行性以及对该人群中HIVST和PrEP摄取的影响。
Pre-exposure prophylaxis (PrEP) is highly effective for HIV prevention, but uptake remains low, especially among adolescent girls and young women (AGYW) in Kenya. A model in which trained AGYW using PrEP deliver HIV self-tests to their close friends and refer them to PrEP may help increase PrEP uptake in this population. To understand AGYW's potential willingness to engage in such a model, we conducted a qualitative formative study in Kenya. We conducted semi-structured in-depth interviews (IDIs) with AGYW (16 to 24 years) in Kiambu County who were determined at risk of HIV acquisition. We purposively recruited “PrEP-naïve” (no prior PrEP use) and “PrEP-experienced” AGYW who used PrEP for at least 1 month within the previous year. We solicited perspectives on initiating/engaging in conversations about HIV risk and PrEP, distributing/receiving HIV self-test kits, and referring/following through on a referral to clinic-based HIV services. We analyzed verbatim transcripts using rapid qualitative analysis and a combination of inductive and deductive approaches, with the latter informed by the Integrated Behavior Model (IBM). From August to December 2020, we conducted 30 IDIs: 15 with PrEP-experienced and 15 with PrEP-naïve AGYW. Participants' median age was 20 [interquartile range (IQR): 20–22]. Overall, most participants anticipated that they would be willing to engage in this model. PrEP-experienced AGYW emphasized the salience of their concerns about friends' HIV risk behaviors, with several noting that they are already in the habit of discussing PrEP with friends. Many additionally expressed positive attitudes toward the proposed target behaviors, perceived these to be normative among AGYW, and expressed confidence in their ability to carry out the behaviors with proper support. Although few participants had HIVST experience, nearly all anticipated they would be able to use an HIV self-test kit correctly if provided instruction. The Kenyan AGYW who participated in this study generally anticipated that they would be willing to engage in a formal peer PrEP referral model enhanced with peer-delivered HIV self-tests. Future research is needed to pilot test this model to determine its acceptability, feasibility, and effect on HIVST and PrEP uptake within this population.
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DOI：
10.1097/qai.0000000000001601
发表时间：
2018-03-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Lippman SA;Lane T;Rabede O;Gilmore H;Chen YH;Mlotshwa N;Maleke K;Marr A;McIntyre JA
通讯作者：
McIntyre JA
影响因子：
4.5
作者：
Matovu JKB;Nambuusi A;Nakabirye S;Wanyenze RK;Serwadda D
通讯作者：
Serwadda D
影响因子：
4.2
作者：
Golden, Shelley D.;Earp, Jo Anne L.
通讯作者：
Earp, Jo Anne L.
影响因子：
3.2
作者：
Wachinger J;Kibuuka Musoke D;Oldenburg CE;Bärnighausen T;Ortblad KF;McMahon SA
通讯作者：
McMahon SA
影响因子：
15.8
作者：
Chanda MM;Ortblad KF;Mwale M;Chongo S;Kanchele C;Kamungoma N;Fullem A;Dunn C;Barresi LG;Harling G;Bärnighausen T;Oldenburg CE
通讯作者：
Oldenburg CE