Moth responses to selectively fluorinated sex pheromone analogs
Moth responses to selectively fluorinated sex pheromone analogs
复制标题
蛾对选择性氟化性信息素类似物的反应
DOI：
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发表时间：
1994
影响因子：
2.3
通讯作者：
R. Waters
中科院分区：
文献类型：
--
作者：
J. Klun;M. Schwarz;N. Wakabayashi;R. Waters
部分氟化类似物的欧洲玉米螟（Ostrinia nubilalis）女性性信息素，11-十四碳烯乙酸酯（97：3 Z：E），具有单-和三氟取代的信息素链的末端碳，模仿的信息素的生物活性，而类似物与氟在任何一侧的双键和五氟类似物基本上是无活性的。这些类似物的信息素活性与先前报道的类似氟化信息素在其他五种蛾的活动比较，揭示了氟取代模式和信息素模仿活性之间不可预测的关系。氟取代模式，使信息素类似物在欧洲玉米螟生物活性无不利影响，在其他物种的信息素活性，匡威亦然。这是一个证据表明，电子质量的网站内的信息素分子的相对重要性不同物种。此外，它表明，生物化学成分（信息素受体蛋白，结合蛋白和酶），使蛾嗅觉化学感受系统也必须在结构上有所不同，从物种到物种，尽管事实上，他们参与嗅觉的化合物具有非常相似的化学结构。
Partially fluorinated analogs of the European corn borer (Ostrinia nubilalis) female sex pheromone, 11-tetradecenyl acetate (97:3Z:E), having mono- and trifluorsubstitutions at the terminal carbon of the pheromone chain, mimicked the biological activity of the pheromone, while analogs with fluorine at either side of the double bond and a pentafluoro analog were essentially inactive. Comparison of the pheromonal activity of these analogs with the previously reported activity of similarly fluorinated pheromones in five other species of moths revealed an unpredictable relationship between fluorine substitution pattern and pheromone-mimicking activity. Fluorine substitution patterns that rendered pheromonal analogs biologically inactive in the European corn borer had no detrimental influence upon pheromonal activity in other species and the converse was also true. This is evidence that the relative importance of electronic qualities of sites within a pheromone molecule differ from species to species. Furthermore, it indicates that the biochemical components (pheromone receptor proteins, binding proteins, and enzymes) that make up moth olfactory chemosensory systems must also vary structurally from species to species, despite the fact that they are involved in olfactory sensing of compounds having very similar chemical structure.
DOI：
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发表时间：
1988
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Vogt,RG;Prestwich,GD;Riddiford,LM
通讯作者：
Riddiford,LM
DOI：
10.1002/neu.480220108
发表时间：
1991-01-01
期刊：
JOURNAL OF NEUROBIOLOGY
影响因子：
--
作者：
VOGT, RG;PRESTWICH, GD;LERNER, MR
通讯作者：
LERNER, MR