Combining behavioral weight loss treatment and a commercial program: a randomized clinical trial.

Combining behavioral weight loss treatment and a commercial program: a randomized clinical trial.
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DOI:
10.1002/oby.20044
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发表时间:
2013-04
期刊:
影响因子:
6.9
通讯作者:
Wing, Rena R.
Wing, Rena R.
中科院分区:
医学2区
文献类型:
--
作者:
Pinto, Angela Marinilli;Fava, Joseph L.;Hoffmann, Debra A.;Wing, Rena R.

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商业减肥计划,如体重观察者(WW)提供广泛认可和可访问的治疗,但通常产生的体重损失是适度的相对于专业提供的计划。本研究检验了一种新的减肥方法的假设,即将专业提供的行为减肥(BWL)治疗的基本组成部分与现有的WW计划相结合,将产生比单独的WW更好的减肥效果;预计新的治疗与单独的BWL之间没有差异。参与者为141名超重和肥胖成人(90%女性,67%非白人,平均年龄= 49.7 ± 9.2岁,平均BMI = 36.2 ± 5.5 kg/m2),随机分配至48周BWL、48周WW或12周BWL后36周WW(联合治疗,CT)。在基线和第12、24和48周进行评估,以体重变化为主要结局。线性混合模型分析显示,治疗组之间的24周体重减轻无显著差异;然而,WW组(M=6.0 kg,SE=0.8)在48周时的体重减轻大于CT组(M=3.6 kg,SE = 0.8; p=0.032),BWL与两者无显著差异(M=5.4 kg,SE=0.8)。此外,与BWL或CT相比,WW参与者在48周时体重下降10%的比例更大(分别为36.7%,13.0%和15.2%,p <0.05)。这项研究表明,WW计划可以产生具有临床意义的体重减轻,并且没有证据表明在WW计划中添加简短的BWL可以改善结局。
Commercial weight loss programs such as Weight Watchers (WW) offer widely recognized and accessible treatment, but typically produce weight losses that are modest relative to professionally delivered programs. This study tested the hypothesis that a novel weight loss approach that combined the fundamental components of professionally delivered behavioral weight loss (BWL) treatment with the existing WW program would produce better weight losses than WW alone; no differences were expected between the novel treatment and BWL alone. Participants were 141 overweight and obese adults (90% women, 67% non-White, mean age = 49.7 ± 9.2 years, mean BMI = 36.2 ± 5.5 kg/m2) randomly assigned to 48 weeks of BWL, 48 weeks of WW, or 12 weeks of BWL followed by 36 weeks of WW (Combined Treatment, CT). Assessments were conducted at baseline and weeks 12, 24, and 48, with weight change as the primary outcome. Linear mixed model analysis showed that 24-week weight losses did not differ significantly between treatment groups; however, weight losses at 48 weeks were greater in the WW group (M=6.0 kg, SE=0.8) compared to the CT group (M=3.6 kg, SE=0.8; p=0.032), with BWL not significantly different from either (M=5.4 kg, SE=0.8). Further, a greater proportion of WW participants lost 10% of baseline weight by 48 weeks compared to BWL or CT (36.7%, 13.0%, and 15.2%, respectively, p’s<0.05). This study shows that the WW program can produce clinically meaningful weight losses and provides no evidence that adding brief BWL to the WW program improves outcome.
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