Poststroke arm and hand paresis: should we target the cervical spinal cord?
Poststroke arm and hand paresis: should we target the cervical spinal cord?
复制标题
中风后手臂和手部麻痹:我们应该针对颈脊髓吗?
DOI:
10.1016/j.tins.2022.05.002
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发表时间:
2022
影响因子:
15.9
通讯作者:
Capogrosso,Marco
中科院分区:
文献类型:
--
作者:
Pirondini,Elvira;Carranza,Erick;Balaguer,Josep-Maria;Sorensen,Erynn;Weber,DouglasJ;Krakauer,JohnW;Capogrosso,Marco
Despite advances in understanding of corticospinal motor control and stroke pathophysiology, current rehabilitation therapies for poststroke upper limb paresis have limited efficacy at the level of impairment. To address this problem, we make the conceptual case for a new treatment approach. We first summarize current understanding of motor control deficits in the arm and hand after stroke and their shared physiological mechanisms with spinal cord injury (SCI). We then review studies of spinal cord stimulation (SCS) for recovery of locomotion after SCI, which provide convincing evidence for enhancement of residual corticospinal function. By extrapolation, we argue for using cervical SCS to restore upper limb motor control after stroke.
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