Multi-site Pain Is Associated with Long-term Patient-Reported Outcomes in Older Adults with Persistent Back Pain.
Multi-site Pain Is Associated with Long-term Patient-Reported Outcomes in Older Adults with Persistent Back Pain.
复制标题
多部位疼痛与持续性背痛老年人的长期患者报告结果相关。
DOI：
10.1093/pm/pny270
复制
发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Jarvik,JeffreyG
中科院分区：
文献类型：
--
作者：
Rundell,SeanD;Patel,KushangV;Krook,MelissaA;Heagerty,PatrickJ;Suri,Pradeep;Friedly,JannaL;Turner,JudithA;Deyo,RichardA;Bauer,Zoya;Nerenz,DavidR;Avins,AndrewL;Nedeljkovic,SrdjanS;Jarvik,JeffreyG
ObjectiveTo estimate the prevalence of co-occurring pain sites among older adults with persistent back pain and associations of multisite pain with longitudinal outcomes.DesignSecondary analysis of a cohort study.SettingThree integrated health systems in the United States.SubjectsEight hundred ninety-nine older adults with persistent back pain.MethodsParticipants reported pain in the following sites: stomach, arms/legs/joints, headaches, neck, pelvis/groin, and widespread pain. Over 18 months, we measured back-related disability (Roland Morris, scored 0–24), pain intensity (11-point numerical rating scale), health-related quality of life (EuroQol-5D [EQ-5D], utility from 0–1), and falls in the past three weeks. We used mixed-effects models to test the association of number and type of pain sites with each outcome.ResultsNearly all (N = 839, 93%) respondents reported at least one additional pain site. There were 216 (24%) with one additional site and 623 (69%) with multiple additional sites. The most prevalent comorbid pain site was the arms/legs/joints (N = 801, 89.1%). Adjusted mixed-effects models showed that for every additional pain site, RMDQ worsened by 0.65 points (95% confidence interval [CI] = 0.43 to 0.86), back pain intensity increased by 0.14 points (95% CI = 0.07 to 0.22), EQ-5D worsened by 0.012 points (95% CI = –0.018 to –0.006), and the odds of falling increased by 27% (odds ratio = 1.27, 95% CI = 1.12 to 1.43). Some specific pain sites (extremity pain, widespread pain, and pelvis/groin pain) were associated with greater long-term disability.ConclusionsMultisite pain is common among older adults with persistent back pain. Number of pain sites was associated with all outcomes; individual pain sites were less consistently associated with outcomes.
登录
查看更多内容
嘌呤霉素对大肠杆菌核糖体光诱导亲和标记的抗生素作用。
影响因子：
2.9
作者：
P. G. Grant;W. A. Strycharz;E. N. Jaynes;B. Cooperman
通讯作者：
B. Cooperman
大肠杆菌核糖体嘌呤霉素位点的光诱导亲和标记。
影响因子：
2.9
作者：
E. N. Jaynes;P. G. Grant;G. Giangrande;R. Wieder;B. Cooperman
通讯作者：
B. Cooperman
氯霉素诱导嘌呤霉素对大肠杆菌核糖体光诱导亲和标记变化的机制研究。
影响因子：
2.9
作者：
G. P. Grant;B. Cooperman;W. A. Strycharz
通讯作者：
W. A. Strycharz
[核糖体的肽基转移酶中心——它是什么？]。
DOI：
10.1016/s0079-6603(08)60130-0
发表时间：
1985
期刊：
Molekuliarnaia biologiia
影响因子：
--
作者：
M. Kukhanova;L. Viktorova
通讯作者：
L. Viktorova
转移 RNA 的结构、功能和进化（附录给出了 178 个 tRNA 的完整序列）。
DOI：
--
发表时间：
1979
期刊：
Progress in Nucleic Acid Research and Molecular Biology
影响因子：
--
作者：
R. Singhal;P. A. Fallis
通讯作者：
P. A. Fallis