PET/computed tomography shows association between subjective pain in knee joints and fluorine-18-fluorodeoxyglucose uptake
PET/computed tomography shows association between subjective pain in knee joints and fluorine-18-fluorodeoxyglucose uptake
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PET/计算机断层扫描显示膝关节主观疼痛与氟-18-氟脱氧葡萄糖摄取之间的关联
DOI：
10.1097/mnm.0000000000001143
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发表时间：
2020
期刊：
影响因子：
1.5
通讯作者：
Takamura N
中科院分区：
文献类型：
--
作者：
Kamasaki T;Mori K;Taira Y;Orita M;Miyamoto I;Usui T;Chiba K;Kudo T;Takamura N
本研究的目的是评估能力的氟-18-氟脱氧葡萄糖（18 F-FDG）-PET/计算机断层扫描（CT）在筛选肌肉骨骼炎症和损伤在knee region.MethodsThe研究包括12名受试者（6男6女）谁抱怨膝关节疼痛休息和94对照谁没有。计算右膝和左膝的最大标准化摄取值（SUV）max，并通过主观膝关节疼痛的4分数字评定量表（NRS）进行比较。SUV值之间的相关性也evaluated.ResultsSUVmax显着高于在膝关节与休息和/或行走疼痛比无痛膝关节。结论18F-FDG-PET/CT对膝关节肌肉骨骼炎症和损伤的筛查有一定的临床价值。由于膝关节疼痛是常见的，特别是在老年人中，我们应该考虑进行进一步的检查时，18 F-FDG摄取确定在膝关节。
ObjectiveThe aim of this study was to evaluate the capability of fluorine-18-fluorodeoxyglucose (18 F-FDG)-PET/computed tomography (CT) in screening for musculoskeletal inflammation and injury in the knee region.MethodsThe study included 12 subjects (6 men and 6 women) who complained of knee pain at rest and 94 controls who did not. Maximum standardized uptake value (SUV) max was calculated for the right and left knees and compared via a 4-point numerical rating scale (NRS) for subjective knee pain. Correlations between SUV values were also evaluated.ResultsSUVmax was significantly higher in knee joints with resting and/or walking pain than in pain-free knee joints. SUVmax in knee joints with walking pain were significantly correlated with NRS category (β= 0.129, P< 0.001).Conclusion18 F-FDG-PET/CT may be useful in screening for musculoskeletal inflammation and injury in the knee region. As knee pain is common, especially among elderly individuals, we should consider conducting further examinations when 18 F-FDG uptake is identified in knee joints.
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