Annual research review: re-thinking the classification of autism spectrum disorders.
Annual research review: re-thinking the classification of autism spectrum disorders.
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DOI：
10.1111/j.1469-7610.2012.02547.x
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发表时间：
2012-05
期刊：
影响因子：
--
通讯作者：
Jones RM
中科院分区：
文献类型：
--
作者：
Lord C;Jones RM
自闭症谱系障碍（ASD）的疾病分类学正处于历史的关键点，因为该领域寻求更好地定义社交沟通缺陷和个体水平上的限制/重复行为的维度，以用于临床和神经生物学目的。这些不同的维度也表明，越来越需要定量测量，准确地映射他们的差异，独立于年龄，语言水平和智商等发展因素。本文综述了ASD患儿的心理测量、临床观察以及遗传学、神经生物学和生理学研究。如何将自闭症沿着维度与类别进行概念化的问题在自闭症疾病分类学以及DSM-5和ICD-11的拟议修改中进行了讨论。新的分类框架纳入了发展方面的差异。至关重要的是要平衡ASD诊断系统中临床实践的需求，以及基于神经生物学的理论，这些理论解决了个体中社交沟通和受限/重复维度之间的关联。澄清术语，改善对ASD核心特征和与之相互作用的其他维度的描述，并为研究和临床目的提供更有效和可靠的方法来量化它们，将推动实践和科学的发展。
The nosology of autism spectrum disorders (ASD) is at a critical point in history as the field seeks to better define dimensions of social-communication deficits and restricted/repetitive behaviors on an individual level for both clinical and neurobiological purposes. These different dimensions also suggest an increasing need for quantitative measures that accurately map their differences, independent of developmental factors such as age, language level and IQ. Psychometric measures, clinical observation as well as genetic, neurobiological and physiological research from toddlers, children and adults with ASD are reviewed. The question of how to conceptualize ASDs along dimensions versus categories is discussed within the nosology of autism and the proposed changes to the DSM-5 and ICD-11. Differences across development are incorporated into the new classification frameworks. It is crucial to balance the needs of clinical practice in ASD diagnostic systems, with neurobiologically based theories that address the associations between social-communication and restricted/repetitive dimensions in individuals. Clarifying terminology, improving description of the core features of ASD and other dimensions that interact with them and providing more valid and reliable ways to quantify them, both for research and clinical purposes, will move forward both practice and science.
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DOI：
10.1352/1944-7558-116.5.381
发表时间：
2011-09-01
影响因子：
2.1
作者：
Anderson, Deborah K.;Maye, Melissa P.;Lord, Catherine
通讯作者：
Lord, Catherine
DOI：
10.1111/1469-7610.00114
发表时间：
2002-10-01
期刊：
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY AND ALLIED DISCIPLINES
影响因子：
--
作者：
Bishop, DVM;Norbury, CF
通讯作者：
Norbury, CF
DOI：
10.1111/j.1469-7610.1992.tb01962.x
发表时间：
1992-07-01
影响因子：
7.6
作者：
BOWLER, DM
通讯作者：
BOWLER, DM
影响因子：
14.5
作者：
Anderson, Jeffrey S.;Nielsen, Jared A.;Lainhart, Janet E.
通讯作者：
Lainhart, Janet E.
影响因子：
3.6
作者：
Anderson, Deborah K.;Oti, Rosalind S.;Welch, Kathleen
通讯作者：
Welch, Kathleen