Concentric rings K-space trajectory for hyperpolarized (13)C MR spectroscopic imaging.
Concentric rings K-space trajectory for hyperpolarized (13)C MR spectroscopic imaging.
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DOI：
10.1002/mrm.25577
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发表时间：
2016-01
影响因子：
3.3
通讯作者：
Larson, Peder E. Z.
中科院分区：
文献类型：
--
作者：
Jiang, Wenwen;Lustig, Michael;Larson, Peder E. Z.
关键词：
建立一种稳健、快速的超极化~(13)C磁共振波谱成像(MRSI)成像技术，并研究其性能。提出了一种用于超极化13C光谱成像的等角速度同心环读出轨迹，并对其特性进行了分析。对几种成像场景的设计权衡进行了定量分析。首次将同心环应用于~(13)C模体和活体动物超极化~(13)C磁共振成像研究，验证了该方法的可行性。最后，给出了一种并行成像加速同心环的研究。与回声平面光谱成像(EPSI)相比，同心环MRSI轨迹具有采集时间短的优点。与EPSI和螺旋技术相比，它提供了足够的频谱带宽和相对较高的SNR效率。Phantom和活体动物研究显示，与EPSI相比，扫描时间减半，图像质量良好，脉动血流伪影减少。平行成像加速同心环在g因子模拟中显示出优于笛卡尔采样的优势，并在超极化13C活体研究中展示了无混叠的图像质量。同心环轨迹是一种稳健而快速的成像技术，非常适合超极化13C磁共振成像的速度、带宽和分辨率要求。
To develop a robust and rapid imaging technique for hyperpolarized 13C MR Spectroscopic Imaging (MRSI) and investigate its performance. A concentric rings readout trajectory with constant angular velocity is proposed for hyperpolarized 13C spectroscopic imaging and its properties are analyzed. Quantitative analyses of design tradeoffs are presented for several imaging scenarios. The first application of concentric rings on 13C phantoms and in vivo animal hyperpolarized 13C MRSI studies were performed to demonstrate the feasibility of the proposed method. Finally, a parallel imaging accelerated concentric rings study is presented. The concentric rings MRSI trajectory has the advantages of acquisition timesaving compared to echo-planar spectroscopic imaging (EPSI). It provides sufficient spectral bandwidth with relatively high SNR efficiency compared to EPSI and spiral techniques. Phantom and in vivo animal studies showed good image quality with half the scan time and reduced pulsatile flow artifacts compared to EPSI. Parallel imaging accelerated concentric rings showed advantages over Cartesian sampling in g-factor simulations and demonstrated aliasing-free image quality in a hyperpolarized 13C in vivo study. The concentric rings trajectory is a robust and rapid imaging technique that fits very well with the speed, bandwidth, and resolution requirements of hyperpolarized 13C MRSI.
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影响因子：
2.2
作者：
Metzger, G;Hu, XP
通讯作者：
Hu, XP
影响因子：
2.9
作者：
Chen, Albert P.;Hurd, Ralph E.;Cunningham, Charles H.
通讯作者：
Cunningham, Charles H.
影响因子：
3.3
作者：
Adalsteinsson, E;Irarrazabal, P;Spielman, DM
通讯作者：
Spielman, DM
影响因子：
3.3
作者：
Moriguchi, H;Duerk, JL
通讯作者：
Duerk, JL
DOI：
10.1007/s10334-009-0169-z
发表时间：
2009-08-01
影响因子：
2.3
作者：
Leupold, Jochen;Mansson, Sven;Wieben, Oliver
通讯作者：
Wieben, Oliver