Pancreatic colloid adenocarcinoma arising from intraductal papillary mucinous neoplasm: Radiologic-pathologic correlation with cinematic rendering.
Pancreatic colloid adenocarcinoma arising from intraductal papillary mucinous neoplasm: Radiologic-pathologic correlation with cinematic rendering.
复制标题
DOI：
10.1177/20584601231157046
复制
发表时间：
2023-02
影响因子：
1.1
通讯作者：
Jeong, Daniel
中科院分区：
文献类型：
--
作者：
Markovitz, Michael;Jiang, Kun;Kim, Daniel;Rose, Trevor;Permuth, Jennifer B.;Jeong, Daniel
胰腺导管内乳头状粘液性肿瘤（IPMN）有可能恶性进展为腺癌。胰腺胶样或粘液性非囊性癌是一种罕见的变异肿瘤，可发生在肠型 IPMN 内，预后相对改善，但可能类似于更致命的管状或导管腺癌。胶样癌是一种浸润性导管上皮肿瘤，主要含有细胞外基质粘蛋白库和少量中央漂浮的肿瘤细胞。虽然一些报告评估了胶体癌独特的病理学和免疫组织化学特征，但文献中的放射学-病理学相关性有限。我们报道了一名 83 岁女性的病例，她因缓慢进展的腹痛而就诊，结果发现患有 IPMN 引起的胶体癌。这是第一份将多模态放射学关联起来的报告之一，包括与该肿瘤相关的电影渲染 (CR) 和组织病理学特征。增强对影像学表现与特定组织病理学结果之间相关性的了解可能有助于这种罕见肿瘤的早期识别和治疗。重点放在 CR，因为这可能有助于指导手术治疗。
Intraductal papillary mucinous neoplasms (IPMN) of the pancreas have the potential for malignant progression into adenocarcinoma. Colloid or mucinous non-cystic carcinoma of the pancreas is an uncommon variant neoplasm that can arise within an intestinal type IPMN and have a relatively improved prognosis but may mimic the more lethal tubular or ductal adenocarcinoma. Colloid carcinoma is an infiltrating ductal epithelial neoplasm containing primarily extracellular stromal mucin pools and scant amount of centrally floating neoplastic cells. While several reports have evaluated the unique pathologic and immunohistochemical profile of colloid carcinomas, there has been limited radiologic–pathologic correlation in the literature. We report a case of an 83-year-old female who presented for evaluation of slowly progressive abdominal pain and was found to have colloid carcinoma arising from an IPMN. This is one of the first reports to correlate the multimodality radiology including cinematic rendering (CR) and histopathology features associated with this tumor. An enhanced understanding of the correlation between imaging appearance and specific histopathologic findings may aid in the early recognition and treatment of this rare neoplasm. Emphasis is placed on CR as this may help guide surgical management.
登录
查看更多内容
影响因子：
2.1
作者：
Youn, Seo Yeon;Rha, Sung Eun;Lee, In Seok
通讯作者：
Lee, In Seok
影响因子：
7.5
作者：
Adsay, NV;Merati, K;Klimstra, DS
通讯作者：
Klimstra, DS
影响因子：
5.6
作者：
Adsay, NV;Merati, K;Klimstra, DS
通讯作者：
Klimstra, DS
影响因子：
120.7
作者：
Regine, William F.;Winter, Kathryn A.;Rich, Tyvin A.
通讯作者：
Rich, Tyvin A.
影响因子：
5.6
作者：
Adsay, NV;Merati, K;Klimstra, DS
通讯作者：
Klimstra, DS