Anhedonia is associated with poor health status and more somatic and cognitive symptoms in patients with coronary artery disease.

Anhedonia is associated with poor health status and more somatic and cognitive symptoms in patients with coronary artery disease.
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DOI:
10.1007/s11136-010-9792-4
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发表时间:
2011-06
影响因子:
3.5
通讯作者:
Denollet, Johan
Denollet, Johan
中科院分区:
医学2区
文献类型:
--
作者:
Pelle, Aline J.;Pedersen, Susanne S.;Erdman, Ruud A. M.;Kazemier, Marten;Spiering, Marquita;van Domburg, Ron T.;Denollet, Johan

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心脏康复(CR)在冠心病(CAD)患者中的有效性受负性情绪和临床因素的调节,但没有研究评估积极情绪的作用。本研究探讨了快感缺乏(即缺乏积极的影响)是否会调节CR对健康状况以及躯体和认知症状的有效性。CAD患者(n = 368)在CR开始时填写医院焦虑和抑郁量表(HADS)以评估快感缺乏,在CR开始时和3个月时填写简明健康调查表(SF-36)和健康投诉量表(HCS)以分别评估健康状况和躯体和认知症状。调整临床和人口统计学因素后,随访期间健康状况显著改善(F(1,357)= 10.84,P = .001)。与非快感缺失患者相比,快感缺失患者的健康状况较差,快感缺失随着时间的推移产生稳定的影响(F(1,358)= 34.80,P <0.001)。躯体和认知症状随时间推移而减少(F(1,358)= 3.85,P = .05)。随着时间的推移,快感缺失者在躯体和认知症状方面的获益更多(F(1,358)= 13.00,P < .001)。快感缺失患者报告CR前后健康状况较差,躯体和认知症状水平较高。随着时间的推移,身体和认知症状作为快感缺失的函数而不同,但健康状况则没有。快感缺失可能为冠心病的二级预防提供一条新的途径。
The effectiveness of cardiac rehabilitation (CR) in patients with coronary artery disease (CAD) is moderated by negative emotions and clinical factors, but no studies evaluated the role of positive emotions. This study examined whether anhedonia (i.e. the lack of positive affect) moderated the effectiveness of CR on health status and somatic and cognitive symptoms. CAD patients (n = 368) filled out the Hospital Anxiety and Depression Scale (HADS) to assess anhedonia at the start of CR, and the Short-Form Health Survey (SF-36) and the Health Complaints Scale (HCS) at the start of CR and at 3 months to assess health status and somatic and cognitive symptoms, respectively. Adjusting for clinical and demographic factors, health status improved significantly during the follow-up (F(1,357) = 10.84, P = .001). Anhedonic patients reported poorer health status compared with non-anhedonic patients, with anhedonia exerting a stable effect over time (F(1,358) = 34.80, P < .001). Somatic and cognitive symptoms decreased over time (F(1,358) = 3.85, P = .05). Anhedonics experienced more benefits in terms of somatic and cognitive symptoms over time (F(1,358) = 13.00, P < .001). Anhedonic patients reported poorer health status and higher levels of somatic and cognitive symptoms prior to and after CR. Somatic and cognitive symptoms differed as a function of anhedonia over time, but health status did not. Anhedonia might provide a new avenue for secondary prevention in CAD.
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