Cell-seeding of periodontal ligament fibroblasts. A novel technique to create new attachment. A pilot study.
Cell-seeding of periodontal ligament fibroblasts. A novel technique to create new attachment. A pilot study.
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牙周膜成纤维细胞的细胞接种。
DOI：
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发表时间：
1991
影响因子：
6.7
通讯作者：
H. Busscher
中科院分区：
文献类型：
--
作者：
L. V. van Dijk;J. Schakenraad;H. T. M. van der Voort;F. Herkströter;H. Busscher
本研究旨在验证种植牙周膜细胞能够形成新附着的假设。在一只比格犬中，去除前磨牙并培养韧带刮片。将培养的牙周膜细胞种植于平整的牙根面，并以粘膜骨膜瓣覆盖。另一侧作为对照。4个月后，处死犬，制备组织学和电子显微镜切片。种子根表面几乎完全覆盖着成牙骨质细胞，而在对照组中，可以观察到上皮向下生长。我们的结论是，种植牙周膜细胞可能是一种创造新结缔组织附着的有前途的技术。
This study was undertaken to test the hypothesis that seeded periodontal ligament cells are able to create new attachment. In one beagle dog, a premolar was removed and scrapings of the ligament were cultured. Artificial periodontal defects were made and the cultured ligament cells were seeded on the planed root surfaces and covered with muco-periosteal flaps. The opposite side served as control. After 4 months, the dog was sacrificed and histological and electron microscopical sections were prepared. The seeded root surfaces were almost completely covered with cementoblasts, whereas in controls, epithelial down-growth could be observed. We conclude that seeding of periodontal ligament cells could be a promising technique to create new connective tissue attachment.
影响因子：
4.3
作者：
MAGNUSSON, I;BATICH, C;COLLINS, BR
通讯作者：
COLLINS, BR