Consensus Statement on High-Intensity Focused Ultrasound for Functional Neurosurgery in Switzerland.
Consensus Statement on High-Intensity Focused Ultrasound for Functional Neurosurgery in Switzerland.
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DOI：
10.3389/fneur.2021.722762
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发表时间：
2021
影响因子：
3.4
通讯作者：
Kaelin-Lang A
中科院分区：
文献类型：
--
作者：
Stieglitz LH;Oertel MF;Accolla EA;Bally J;Bauer R;Baumann CR;Benninger D;Bohlhalter S;Büchele F;Hägele-Link S;Kägi G;Krack P;Krüger MT;Mahendran S;Möller JC;Mylius V;Piroth T;Werner B;Kaelin-Lang A
背景资料：磁共振引导高强度聚焦超声（MRgHiFUS）已发展成为功能性神经外科手术的可行消融治疗选择。然而，目前尚不清楚这项新技术应如何整合到当前和已建立的临床实践中，并应就推荐的适应症、立体定向靶点、患者选择和结局测量达成共识。目的：总结和统一瑞士神经和神经外科界关于MRgHiFUS干预脑部疾病的现有知识和临床经验，作为国家共识文件发表。研究方法：18名在瑞士从事运动障碍领域工作的经验丰富的神经外科医生和神经学家以及代表12个瑞士临床中心和5个医学协会的15个部门的一名健康物理学家参加了研讨会，并为共识文件做出了贡献。所有专家都有当前治疗方式或MRgHiFUS的经验。他们应邀参加了两次研讨会和共识会议以及一次在线会议。作为研讨会筹备工作的一部分，对文献进行了全面的审查，并向与会者分发了一份相关讨论议题清单。特别强调了当前的经验和实践，以及有关MRgHiFUS在功能神经外科临床应用的争议领域。结果如下：这些建议涉及一般脑部疾病治疗的损伤，以及MRgHiFUS适应症、立体定向靶点、治疗替代方案、患者选择和管理、报告和随访的标准化以及运动障碍介入治疗国家登记的初始化。良好的临床证据目前仅可用于单侧丘脑病变治疗特发性震颤或震颤主导型帕金森病，以及在较小程度上用于单侧丘脑底核切开术治疗帕金森病运动功能。然而，研究者明确建议进一步探索和调整基于MRgHiFUS的功能性病变干预措施，并确认需要基于统一登记系统对这些方法进行基于结果的评价。MRgHiFUS和DBS应由熟悉这两种方法的专家进行评估，因为它们是相互补充的治疗选择，具有独特的优势和潜力。结论：这篇多学科共识论文是瑞士功能神经外科MRgHiFUS治疗安全实施和标准化实践的代表性建议。
Background: Magnetic resonance-guided high-intensity focused ultrasound (MRgHiFUS) has evolved into a viable ablative treatment option for functional neurosurgery. However, it is not clear yet, how this new technology should be integrated into current and established clinical practice and a consensus should be found about recommended indications, stereotactic targets, patient selection, and outcome measurements. Objective: To sum up and unify current knowledge and clinical experience of Swiss neurological and neurosurgical communities regarding MRgHiFUS interventions for brain disorders to be published as a national consensus paper. Methods: Eighteen experienced neurosurgeons and neurologists practicing in Switzerland in the field of movement disorders and one health physicist representing 15 departments of 12 Swiss clinical centers and 5 medical societies participated in the workshop and contributed to the consensus paper. All experts have experience with current treatment modalities or with MRgHiFUS. They were invited to participate in two workshops and consensus meetings and one online meeting. As part of workshop preparations, a thorough literature review was undertaken and distributed among participants together with a list of relevant discussion topics. Special emphasis was put on current experience and practice, and areas of controversy regarding clinical application of MRgHiFUS for functional neurosurgery. Results: The recommendations addressed lesioning for treatment of brain disorders in general, and with respect to MRgHiFUS indications, stereotactic targets, treatment alternatives, patient selection and management, standardization of reporting and follow-up, and initialization of a national registry for interventional therapies of movement disorders. Good clinical evidence is presently only available for unilateral thalamic lesioning in treating essential tremor or tremor-dominant Parkinson's disease and, to a minor extent, for unilateral subthalamotomy for Parkinson's disease motor features. However, the workgroup unequivocally recommends further exploration and adaptation of MRgHiFUS-based functional lesioning interventions and confirms the need for outcome-based evaluation of these approaches based on a unified registry. MRgHiFUS and DBS should be evaluated by experts familiar with both methods, as they are mutually complementing therapy options to be appreciated for their distinct advantages and potential. Conclusion: This multidisciplinary consensus paper is a representative current recommendation for safe implementation and standardized practice of MRgHiFUS treatments for functional neurosurgery in Switzerland.
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晚期帕金森病的自适应深脑刺激。
影响因子：
11.2
作者：
Little, Simon;Pogosyan, Alex;Neal, Spencer;Zavala, Baltazar;Zrinzo, Ludvic;Hariz, Marwan;Foltynie, Thomas;Limousin, Patricia;Ashkan, Keyoumars;FitzGerald, James;Green, Alexander L.;Aziz, Tipu Z.;Brown, Peter
通讯作者：
Brown, Peter
影响因子：
11.2
作者：
Chang, Jin Woo;Park, Chang Kyu;Elias, W. Jeffrey
通讯作者：
Elias, W. Jeffrey
影响因子：
25.8
作者：
Lopes, Antonio C.;Greenberg, Benjamin D.;Miguel, Euripedes C.
通讯作者：
Miguel, Euripedes C.
影响因子：
158.5
作者：
Martinez-Fernandez, Raul;Manez-Miro, Jorge U.;Obeso, Jose A.
通讯作者：
Obeso, Jose A.
DOI：
10.1002/mds.115
发表时间：
2018-12
期刊：
Movement disorders : official journal of the Movement Disorder Society
影响因子：
--
作者：
Habets JGV;Heijmans M;Kuijf ML;Janssen MLF;Temel Y;Kubben PL
通讯作者：
Kubben PL