An update on adaptive deep brain stimulation in Parkinson's disease.
An update on adaptive deep brain stimulation in Parkinson's disease.
复制标题
DOI:
10.1002/mds.115
复制
发表时间:
2018-12
期刊:
影响因子:
--
通讯作者:
Kubben PL
中科院分区:
文献类型:
--
作者:
Habets JGV;Heijmans M;Kuijf ML;Janssen MLF;Temel Y;Kubben PL
Advancing conventional open‐loop DBS as a therapy for PD is crucial for overcoming important issues such as the delicate balance between beneficial and adverse effects and limited battery longevity that are currently associated with treatment. Closed‐loop or adaptive DBS aims to overcome these limitations by real‐time adjustment of stimulation parameters based on continuous feedback input signals that are representative of the patient's clinical state. The focus of this update is to discuss the most recent developments regarding potential input signals and possible stimulation parameter modulation for adaptive DBS in PD. Potential input signals for adaptive DBS include basal ganglia local field potentials, cortical recordings (electrocorticography), wearable sensors, and eHealth and mHealth devices. Furthermore, adaptive DBS can be applied with different approaches of stimulation parameter modulation, the feasibility of which can be adapted depending on specific PD phenotypes. Implementation of technological developments like machine learning show potential in the design of such approaches; however, energy consumption deserves further attention. Furthermore, we discuss future considerations regarding the clinical implementation of adaptive DBS in PD. © 2018 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.
登录
查看更多内容
DOI:
10.3233/jpd-171077
发表时间:
2017
期刊:
Journal of Parkinson's disease
影响因子:
--
作者:
Dayal V;Limousin P;Foltynie T
通讯作者:
Foltynie T
影响因子:
3.7
作者:
Broen MP;Marsman VA;Kuijf ML;Van Oostenbrugge RJ;van Os J;Leentjens AF
通讯作者:
Leentjens AF
影响因子:
4.1
作者:
Chang, Su-Youne;Kimble, Christopher J.;Lee, Kendall H.
通讯作者:
Lee, Kendall H.
影响因子:
2.4
作者:
Bayes, Angels;Samba, Albert;Cabestany, Joan
通讯作者:
Cabestany, Joan
影响因子:
5.3
作者:
Chen, Chiung Chu;Hsu, Yi Ting;Brown, Peter
通讯作者:
Brown, Peter