Plant-based diet index and erectile dysfunction in the Health Professionals Follow-Up Study.
Plant-based diet index and erectile dysfunction in the Health Professionals Follow-Up Study.
复制标题
DOI：
10.1111/bju.15765
复制
发表时间：
2022-10
影响因子：
4.5
通讯作者：
Bauer, Scott R.
中科院分区：
文献类型：
--
作者：
Yang, Heiko;Breyer, Benjamin N.;Rimm, Eric B.;Giovannucci, Edward;Loeb, Stacy;Kenfield, Stacey A.;Bauer, Scott R.
饮食模式会影响患勃起功能障碍（ED）的风险。目前尚不清楚具有健康和环境益处的植物性饮食是否与ED有关。本研究的目的是评估植物性饮食指数评分与ED事件之间的纵向关联。我们对21,942名年龄在40至75岁之间的男性进行了前瞻性分析，这些男性参加了健康专业人员随访研究。从2000年开始，ED每四年进行一次问卷评估。饮食数据通过每四年完成一次的有效食物频率问卷收集，并用于计算总植物性饮食指数（PDI）评分，以及健康（hPDI）和不健康（uPDI）评分。多变量Cox比例风险模型用于计算突发ED的风险比（HR）。所有模型均按年龄（<60岁、60至<70岁、≥70岁）分层。在60岁至70岁以下的男性中，hPDI与ED的发病率呈负相关。在该年龄组中，与最低五分位数的患者相比，hPDI最高五分位数的患者患ED的风险降低18% （HR = 0.82; 95% CI 0.73-0.91； p趋势<0.001）。相反，60岁以下男性的uPDI与ED呈正相关（HR = 1.27; 95% CI 1.01-1.60; P-trend=0.02）。鼓励健康的植物性饮食可能是对维持勃起功能感兴趣的男性的环境可持续干预。
Dietary patterns can influence the risk of developing erectile dysfunction (ED). It is unknown whether plant-based diets, which have known health and environmental benefits, are associated with ED. The aim of this study was to evaluate the longitudinal association between plant-based diet index scores and incident ED. We conducted a prospective analysis of 21,942 men aged 40 to 75 years who were enrolled in the Health Professionals Follow-Up Study. ED was assessed with questionnaires every four years starting in 2000. Dietary data were collected via validated food frequency questionnaires completed every four years and were used to calculate total plant-based diet index (PDI) scores, as well as healthy (hPDI) and unhealthy (uPDI) subscores. Multivariable Cox proportional hazards models were used to compute hazard ratios (HR) for incident ED. All models were stratified by age (<60, 60 to <70, ≥70 years). hPDI was inversely associated with incident ED among men aged 60 to <70. Those in the highest quintile of hPDI in that age group had an 18% lower risk of ED (HR = 0.82; 95% CI 0.73–0.91; P-trend<0.001) compared to those in the lowest quintile. Conversely, uPDI was positively associated with ED in men aged <60 (HR = 1.27; 95% CI 1.01–1.60; P-trend=0.02). Encouraging a healthy plant-based diet may be an environmentally sustainable intervention for men interested in maintaining erectile function.
登录
查看更多内容
影响因子：
13.8
作者：
Bauer SR;Breyer BN;Stampfer MJ;Rimm EB;Giovannucci EL;Kenfield SA
通讯作者：
Kenfield SA
影响因子：
5.4
作者：
De Backer, Charlotte;Erreygers, Sara;Van Bauwel, Sofie
通讯作者：
Van Bauwel, Sofie
影响因子：
5.7
作者：
Litwin, MS;Nied, RJ;Dhanani, N
通讯作者：
Dhanani, N
影响因子：
5.4
作者：
Ladapo JA;Hoffmann U;Lee KL;Coles A;Huang M;Mark DB;Dolor RJ;Pelberg RA;Budoff M;Sigurdsson G;Severance HW;Douglas PS
通讯作者：
Douglas PS
影响因子：
7.1
作者：
Loeb, Stacy;Fu, Benjamin C.;Mucci, Lorelei A.
通讯作者：
Mucci, Lorelei A.