A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration.
A Muscle Stem Cell Support Group: Coordinated Cellular Responses in Muscle Regeneration.
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DOI:
10.1016/j.devcel.2018.06.018
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发表时间:
2018-07-16
影响因子:
11.8
通讯作者:
Rando TA
中科院分区:
文献类型:
--
作者:
Wosczyna MN;Rando TA
Skeletal muscle has an extraordinary regenerative capacity due to the activity of tissue-specific muscle stem cells (MuSCs). Consequently, these cells have received the most attention in studies investigating the cellular processes of skeletal muscle regeneration. However, efficient capacity to rebuild this tissue also depends on additional cells in the local milieu, as disrupting their normal contributions often leads to incomplete regeneration. Here, we review these additional cells that contribute to the regenerative process. Understanding the complex interactions between and among these cell populations has the potential to lead to therapies that will help promote normal skeletal muscle regeneration under conditions where this process is suboptimal.
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影响因子:
56.9
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通讯作者:
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