Effect of symptoms on physical performance in COPD.
Effect of symptoms on physical performance in COPD.
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DOI：
10.1016/j.hrtlng.2017.12.007
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发表时间：
2018-03
期刊：
影响因子：
--
通讯作者：
Fan VS
中科院分区：
文献类型：
--
作者：
Lee J;Nguyen HQ;Jarrett ME;Mitchell PH;Pike KC;Fan VS
慢性阻塞性肺疾病（Chronic obstructive pulmonary disease， COPD）患者会出现呼吸困难、焦虑、抑郁、疲劳等多种症状，这些症状之间存在高度相关性。这些症状加在一起可能会导致身体机能受损。本研究的目的是研究呼吸困难、焦虑、抑郁症状和疲劳作为COPD患者身体表现的影响因素之间的相互关系。本研究使用了282例COPD患者的基线数据，这些数据来自一项纵向观察研究，旨在探索抑郁、炎症和功能状态之间的关系。数据分析包括验证性因子分析和结构方程模型。呼吸困难、焦虑和抑郁对疲劳有直接影响，呼吸困难和焦虑均对体能有直接影响。较高水平的呼吸困难与身体机能受损显著相关，而较高水平的焦虑与身体机能增强显著相关。呼吸困难是COPD患者身体机能受损的最强预测因子。
Chronic obstructive pulmonary disease (COPD) patients experience multiple symptoms including dyspnea, anxiety, depression, and fatigue, which are highly correlated with each other. Together, those symptoms may contribute to impaired physical performance. The purpose of this study was to examine interrelationships among dyspnea, anxiety, depressive symptoms, and fatigue as contributing factors to physical performance in COPD. This study used baseline data of 282 COPD patients from a longitudinal observational study to explore the relationship between depression, inflammation, and functional status. Data analyses included confirmatory factor analyses and structural equation modeling. Dyspnea, anxiety and depression had direct effects on fatigue, and both dyspnea and anxiety had direct effects on physical performance. Higher levels of dyspnea were significantly associated with impaired physical performance whereas higher levels of anxiety were significantly associated with enhanced physical performance. Dyspnea was the strongest predictor of impaired physical performance in patients with COPD.
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影响因子：
2
作者：
Doyle T;Palmer S;Johnson J;Babyak MA;Smith P;Mabe S;Welty-Wolf K;Martinu T;Blumenthal JA
通讯作者：
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影响因子：
4.3
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通讯作者：
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影响因子：
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作者：
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通讯作者：
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