The confluence of stereotactic ablative radiotherapy and tumor immunology.
The confluence of stereotactic ablative radiotherapy and tumor immunology.
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DOI：
10.1155/2011/439752
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发表时间：
2011
影响因子：
--
通讯作者：
Wilson GD
中科院分区：
文献类型：
--
作者：
Finkelstein SE;Timmerman R;McBride WH;Schaue D;Hoffe SE;Mantz CA;Wilson GD
Stereotactic radiation approaches are gaining more popularity for the treatment of intracranial as well as extracranial tumors in organs such as the liver and lung. Technology, rather than biology, is driving the rapid adoption of stereotactic body radiation therapy (SBRT), also known as stereotactic ablative radiotherapy (SABR), in the clinic due to advances in precise positioning and targeting. Dramatic improvements in tumor control have been demonstrated; however, our knowledge of normal tissue biology response mechanisms to large fraction sizes is lacking. Herein, we will discuss how SABR can induce cellular expression of MHC I, adhesion molecules, costimulatory molecules, heat shock proteins, inflammatory mediators, immunomodulatory cytokines, and death receptors to enhance antitumor immune responses.
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通过淋巴结消除来清除稳态细胞因子下沉，增强了采用转移的肿瘤特异性CD8+ T细胞的功效。
影响因子：
15.3
作者：
Gattinoni, Luca;Finkelstein, Steven E;Klebanoff, Christopher A;Antony, Paul A;Palmer, Douglas C;Spiess, Paul J;Hwang, Leroy N;Yu, Zhiya;Wrzesinski, Claudia;Heimann, David M;Surh, Charles D;Rosenberg, Steven A;Restifo, Nicholas P
通讯作者：
Restifo, Nicholas P
DOI：
10.1158/1078-0432.ccr-09-0265
发表时间：
2009-09-01
期刊：
Clinical cancer research : an official journal of the American Association for Cancer Research
影响因子：
--
作者：
Dewan MZ;Galloway AE;Kawashima N;Dewyngaert JK;Babb JS;Formenti SC;Demaria S
通讯作者：
Demaria S
DOI：
10.1016/j.ijrobp.2009.12.074
发表时间：
2010-07-01
影响因子：
7
作者：
Cho, Jaeho;Kodym, Reinhard;Story, Michael D.
通讯作者：
Story, Michael D.
影响因子：
3.5
作者：
Kirkpatrick, John P.;Meyer, Jeffrey J.;Marks, Lawrence B.
通讯作者：
Marks, Lawrence B.
影响因子：
5.4
作者：
HOWIE, S;MCBRIDE, WH
通讯作者：
MCBRIDE, WH