Composite 3D printing of biomimetic human teeth.

Composite 3D printing of biomimetic human teeth.
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DOI:
10.1038/s41598-022-11658-y
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发表时间:
2022-05-12
期刊:
影响因子:
4.6
通讯作者:
Barber, A. H.
Barber, A. H.
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Cresswell-Boyes, A. J.;Davis, G. R.;Krishnamoorthy, M.;Mills, D.;Barber, A. H.

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人类牙齿通过材料和形态的复杂结构复合组织而具有机械坚固性。在人造牙齿(typodont牙齿)中复制机械功能的努力,例如在牙科训练应用中,试图复制真实牙齿的结构和形态,但在牙齿的机械切割过程中缺乏触觉相似性。在这项研究中,利用一种开发新型复合材料的方法 3D 打印了仿生错牙牙,其形态源自拔除牙齿的 X 射线显微断层扫描。这些复合材料在甲基丙烯酸酯基光聚合物树脂中含有一系列玻璃、羟基磷灰石和陶瓷增强材料,与六颗商用人造牙列进行了比较。使用测量所施加切削力的触觉方法来评估拔除的人类牙齿和 3D 打印的错字牙齿的机械性能。结果表明,尽管材料成分与人类牙齿中发现的材料不同,但复制牙釉质和牙本质的 3D 打印错牙牙齿在机械性能上可与拔出的人类牙齿相媲美。材料弹性模量和硬度的多参数变量被用来描述切割人类和仿生物体时的触觉响应,强调了在确定切削力作用下牙齿机械性能时,材料机械性能的比率与非绝对材料性能之间的关键依赖性。
Human teeth are mechanically robust through a complex structural composite organisation of materials and morphology. Efforts to replicate mechanical function in artificial teeth (typodont teeth), such as in dental training applications, attempt to replicate the structure and morphology of real teeth but lack tactile similarities during mechanical cutting of the teeth. In this study, biomimetic typodont teeth, with morphology derived from X-ray microtomography scans of extracted teeth, were 3D printed using an approach to develop novel composites. These composites with a range of glass, hydroxyapatite and porcelain reinforcements within a methacrylate-based photopolymer resin were compared to six commercial artificial typodont teeth. Mechanical performance of the extracted human teeth and 3D printed typodont teeth were evaluated using a haptic approach of measuring applied cutting forces. Results indicate 3D printed typodont teeth replicating enamel and dentine can be mechanically comparable to extracted human teeth despite the material compositions differing from the materials found in human teeth. A multiple parameter variable of material elastic modulus and hardness is shown to describe the haptic response when cutting through both human and biomimetic, highlighting a critical dependence between the ratio of material mechanical properties and not absolute material properties in determining tooth mechanical performance under the action of cutting forces.
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