Adherence to HIV care after pregnancy among women in sub-Saharan Africa: falling off the cliff of the treatment cascade.

Adherence to HIV care after pregnancy among women in sub-Saharan Africa: falling off the cliff of the treatment cascade.
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DOI:
10.1007/s11904-014-0252-6
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发表时间:
2015-03
影响因子:
4.6
通讯作者:
Smit, Jennifer A.
Smit, Jennifer A.
中科院分区:
医学2区
文献类型:
--
作者:
Psaros, Christina;Remmert, Jocelyn E.;Bangsberg, David R.;Safren, Steven A.;Smit, Jennifer A.

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检测和治疗机会的增加意味着艾滋病毒可以作为一种慢性疾病进行管理,尽管成功的管理需要医疗保健系统的持续参与。 Most of the global HIV burden is in sub-Saharan Africa where rates of new infections are consistently higher in women versus men. Pregnancy is often the point at which an HIV diagnosis is made.虽然预防母婴传播干预措施可显着降低艾滋病毒垂直传播率,但妇女必须为其婴儿注射抗逆转录病毒药物、遵守母乳喂养建议,并在分娩后对婴儿进行艾滋病毒检测。一些妇女应继续服用怀孕期间开始的抗逆转录病毒药物,而其他妇女则应进行常规检测,以便在适当的时候重新开始治疗。产后期对持续治疗依从性和参与护理存在许多障碍。虽然一些研究考察了产后预防母婴传播指南的遵守情况,但很少有研究关注母亲持续参与的护理,也很少研究超过六周产后访视的遵守情况。在这里,我们试图找出研究文献中的差距,并就如何解决持续产后艾滋病毒护理的障碍提出建议。
Increased access to testing and treatment means HIV can be managed as a chronic illness, though successful management requires continued engagement with the healthcare system. Most of the global HIV burden is in sub-Saharan Africa where rates of new infections are consistently higher in women versus men. Pregnancy is often the point at which an HIV diagnosis is made. While PMTCT interventions significantly reduce the rate of vertical transmission of HIV, women must administer ARVs to their infants, adhere to breastfeeding recommendations, and test their infants for HIV after childbirth. Some women will be expected to remain on the ARVs initiated during the pregnancy period, while others are expected to engage in routine testing so treatment can be reinitiated when appropriate. The postpartum period presents many barriers to sustained treatment adherence and engagement in care. While some studies have examined adherence to postpartum PMTCT guidelines, few have focused on continued engagement in care by the mother, and very few examine adherence beyond the six week postpartum visit. Here, we attempt to identify gaps in the research literature and make recommendations on how to address barriers to ongoing postpartum HIV care.
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