Structural basis for exon recognition by a group II intron.
Structural basis for exon recognition by a group II intron.
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DOI:
10.1038/nsmb.1509
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发表时间:
2008-11
影响因子:
16.8
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中科院分区:
文献类型:
--
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Free group II introns are infectious retroelements that can bind and insert themselves into RNA and DNA molecules via reverse-splicing. Here we report the 3.4Å crystal structure of a complex between an oligonucleotide target substrate and a group IIC intron, as well as the refined free intron structure. The structure of the complex reveals the conformation of motifs involved in exon recognition by group II introns.
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