Association of Race and Ethnicity With COVID-19 Outcomes in Rheumatic Disease: Data From the COVID-19 Global Rheumatology Alliance Physician Registry.
Association of Race and Ethnicity With COVID-19 Outcomes in Rheumatic Disease: Data From the COVID-19 Global Rheumatology Alliance Physician Registry.
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DOI：
10.1002/art.41567
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发表时间：
2021-03
期刊：
影响因子：
--
通讯作者：
COVID-19 Global Rheumatology Alliance
中科院分区：
文献类型：
--
作者：
Gianfrancesco MA;Leykina LA;Izadi Z;Taylor T;Sparks JA;Harrison C;Trupin L;Rush S;Schmajuk G;Katz P;Jacobsohn L;Hsu TY;D'Silva KM;Serling-Boyd N;Wallwork R;Todd DJ;Bhana S;Costello W;Grainger R;Hausmann JS;Liew JW;Sirotich E;Sufka P;Wallace ZS;Machado PM;Robinson PC;Yazdany J;COVID-19 Global Rheumatology Alliance
在美国总人口中，少数族裔经历了2019年冠状病毒病(新冠肺炎)的更严重后果。这项研究旨在研究风湿病患者中种族/民族与新冠肺炎住院时间、通风状况和死亡率之间的关系。2020年3月24日至2020年8月26日期间，美国风湿病患者和新冠肺炎注册到新冠肺炎全球风湿病联盟医生注册。种族/民族被定义为白人、非裔美国人、拉丁裔、亚洲人或其他/混合种族。结果测量包括住院时间、是否需要呼吸机支持和死亡。多变量回归模型被用来估计优势比(OR)和根据年龄、性别、吸烟状况、风湿病诊断、合并症、感染前用药和风湿病活动调整后的95%可信区间(95%CI)。共纳入1324名患者，其中36%住院，6%死亡；26%的住院患者需要机械通气。在多变量模型中，与白人患者相比，非洲裔美国人患者(OR 2.74[95%CI 1.90-3.95])、拉丁裔患者(OR 1.71[95%CI 1.18-2.49])和亚裔患者(OR 2.69[95%CI 1.16-6.24])的住院几率更高。拉丁裔患者需要呼吸机支持的几率也增加了3倍(OR 3.25[95%CI 1.75-6.05])。没有发现基于种族/民族的死亡率差异，尽管检测关联的能力可能有限。与美国普通人群的研究结果相似，患有风湿病和新冠肺炎的少数族裔患者住院和呼吸机支持的几率更高。这些结果说明了风湿病患者中与新冠肺炎相关的显著健康差异。风湿病界应积极应对目前在大流行期间经历不公平健康结果的患者的需求。
Racial/ethnic minorities experience more severe outcomes of coronavirus disease 2019 (COVID-19) in the general US population. This study was undertaken to examine the association between race/ethnicity and COVID-19 hospitalization, ventilation status, and mortality in people with rheumatic disease. US patients with rheumatic disease and COVID-19 were entered into the COVID-19 Global Rheumatology Alliance physician registry between March 24, 2020 and August 26, 2020 were included. Race/ethnicity was defined as White, African American, Latinx, Asian, or other/mixed race. Outcome measures included hospitalization, requirement for ventilatory support, and death. Multivariable regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (95% CIs) adjusted for age, sex, smoking status, rheumatic disease diagnosis, comorbidities, medication use prior to infection, and rheumatic disease activity. A total of 1,324 patients were included, of whom 36% were hospitalized and 6% died; 26% of hospitalized patients required mechanical ventilation. In multivariable models, African American patients (OR 2.74 [95% CI 1.90–3.95]), Latinx patients (OR 1.71 [95% CI 1.18–2.49]), and Asian patients (OR 2.69 [95% CI 1.16–6.24]) had higher odds of hospitalization compared to White patients. Latinx patients also had 3-fold increased odds of requiring ventilatory support (OR 3.25 [95% CI 1.75–6.05]). No differences in mortality based on race/ethnicity were found, though power to detect associations may have been limited. Similar to findings in the general US population, racial/ethnic minorities with rheumatic disease and COVID-19 had increased odds of hospitalization and ventilatory support. These results illustrate significant health disparities related to COVID-19 in people with rheumatic diseases. The rheumatology community should proactively address the needs of patients currently experiencing inequitable health outcomes during the pandemic.
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影响因子：
15.1
作者：
Lassale, Camille;Gaye, Bamba;Batty, G. David
通讯作者：
Batty, G. David
DOI：
10.1002/art.41450
发表时间：
2020-12
期刊：
Arthritis & rheumatology (Hoboken, N.J.)
影响因子：
--
作者：
Fernandez-Ruiz R;Masson M;Kim MY;Myers B;Haberman RH;Castillo R;Scher JU;Guttmann A;Carlucci PM;Deonaraine KK;Golpanian M;Robins K;Chang M;Belmont HM;Buyon JP;Blazer AD;Saxena A;Izmirly PM;NYU WARCOV Investigators
通讯作者：
NYU WARCOV Investigators
影响因子：
4.4
作者：
Mahajan, Uma, V;Larkins-Pettigrew, Margaret
通讯作者：
Larkins-Pettigrew, Margaret
影响因子：
4.7
作者：
Barton, J. L.;Trupin, L.;Yelin, E.
通讯作者：
Yelin, E.
DOI：
10.15585/mmwr.mm6927a3
发表时间：
2020-07-10
期刊：
MMWR. Morbidity and mortality weekly report
影响因子：
--
作者：
Hsu HE;Ashe EM;Silverstein M;Hofman M;Lange SJ;Razzaghi H;Mishuris RG;Davidoff R;Parker EM;Penman-Aguilar A;Clarke KEN;Goldman A;James TL;Jacobson K;Lasser KE;Xuan Z;Peacock G;Dowling NF;Goodman AB
通讯作者：
Goodman AB