Changing incidence of hepatocellular carcinoma in Japan.
Changing incidence of hepatocellular carcinoma in Japan.
复制标题
日本肝细胞癌发病率的变化。
作者：
K. Okuda;I. Fujimoto;A. Hanai;Y. Urano
根据大阪癌症登记处（1981年人口8,512,351人）1963-1983年期间的数据、日本人口统计、卫生和福利部以及日本尸检登记处的数据，研究了日本肝细胞癌（HCC）发病率的趋势，这些数据包含了1958 -1983年26年间594,132例单独归档的病例。癌症登记数据和尸检记录都显示，HCC的发病率增加了2倍以上，尤其是在过去10年左右的时间里，男性的发病率增加了2倍以上，而女性的发病率增加不太明显。长崎市和宫城县的癌症登记处以及人口统计局也证实了同样的趋势。结合尸检资料研究发现，1958-1961年肝硬化无HCC与HCC（伴肝硬化和不伴肝硬化）尸检数量大致相同，目前（1980-1983年）后者约为前者的2倍。慢性非甲、非乙型肝炎是肝硬化患者生存期延长以外HCC发病率增加的可能原因之一。
A trend in the incidence of hepatocellular carcinoma (HCC) in Japan was studied from the data of the Osaka Cancer Registry (population, 8,512,351 in 1981) for the period of 1963-1983, the Vital Statistics of Japan, Ministry of Health and Welfare, and the Japan Autopsy Registry which contained 594,132 individually filed cases in the 26-year period from 1958 to 1983. Both cancer registry data and autopsy records showed a more than 2-fold increase in HCC incidence, particularly in the last 10 years or so, among males and a less pronounced increase in females. The same trend was borne out by the cancer registries of Nagasaki City and Miyagi Prefecture and the Vital Statistics. When studied with the autopsy data, it was found that the numbers of autopsies for cirrhosis without HCC and autopsies for HCC (with and without cirrhosis) were about the same in 1958-1961 and that currently (1980-1983) the latter is about 2 times the former. As one of the possible causes of increase in HCC incidence other than prolonged survival of patients with cirrhosis, chronic non-A, non-B hepatitis is discussed.
非甲非乙型输血后肝炎——十年后。
影响因子：
29.4
作者：
Koretz,RL;Stone,O;Mousa,M;Gitnick,GL
通讯作者：
Gitnick,GL