Nausea and vomiting in gastroparesis: similarities and differences in idiopathic and diabetic gastroparesis.
Nausea and vomiting in gastroparesis: similarities and differences in idiopathic and diabetic gastroparesis.
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DOI：
10.1111/nmo.12893
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发表时间：
2016-12
影响因子：
3.5
通讯作者：
NIDDK Gastroparesis Clinical Research Consortium (GpCRC)
中科院分区：
文献类型：
--
作者：
Parkman HP;Hallinan EK;Hasler WL;Farrugia G;Koch KL;Calles J;Snape WJ;Abell TL;Sarosiek I;McCallum RW;Nguyen L;Pasricha PJ;Clarke J;Miriel L;Lee L;Tonascia J;Hamilton F;NIDDK Gastroparesis Clinical Research Consortium (GpCRC)
Nausea and vomiting are classic symptoms of gastroparesis. It is unclear if characteristics of nausea and vomiting are similar in different etiologies of gastroparesis. Describe characteristics of nausea and vomiting in patients with gastroparesis; and determine if there are differences in nausea and vomiting in diabetic (DG) and idiopathic gastroparesis (IG). Gastroparetic patients enrolling in the NIDDK Gastroparesis Registry underwent assessment with history and questionnaires assessing symptoms, quality of life, and a questionnaire characterizing nausea and vomiting. Of 159 gastroparesis patients (107 IG, 52 DG), 96% experienced nausea while 65% experienced vomiting. Nausea was predominant symptom in 28% and vomiting was predominant in 4%. Nausea was severe or very severe in 41%. PAGI-SYM nausea/vomiting subscore was greater with increased vomiting severity, but not nausea severity in DG than IG. Nausea was related to meals in 71%; lasting most of the day in 41%. Increasing nausea severity was related to decreased quality of life. Nausea often preceded vomiting in 82% of patients and vomiting often relieved nausea in 30%. Vomiting was more common in DG (81%) compared to IG (57%; p=0.004). Diabetic patients more often had vomiting in the morning before eating, during the night, and when not eating. Nausea is present in essentially all patients with gastroparesis irrespective of cause and associated with decreased quality of life. In contrast, vomiting was more prevalent, more severe, and occurred more often in DG than IG. Thus, characteristics of vomiting differ in idiopathic versus diabetic gastroparesis.
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影响因子：
29.4
作者：
Parkman HP;Yates K;Hasler WL;Nguyen L;Pasricha PJ;Snape WJ;Farrugia G;Koch KL;Abell TL;McCallum RW;Lee L;Unalp-Arida A;Tonascia J;Hamilton F;National Institute of Diabetes and Digestive and Kidney Diseases Gastroparesis Clinical Research Consortium
通讯作者：
National Institute of Diabetes and Digestive and Kidney Diseases Gastroparesis Clinical Research Consortium
影响因子：
7.6
作者：
Revicki, DA;Rentz, AM;Tack, J
通讯作者：
Tack, J
影响因子：
9.8
作者：
Hasler, William L.;Parkman, Henry P.;Wilson, Laura A.;Pasricha, Pankaj J.;Koch, Kenneth L.;Abell, Thomas L.;Snape, William J.;Farrugia, Gianrico;Lee, Linda;Tonascia, James;Unalp-Arida, Aynur;Hamilton, Frank
通讯作者：
Hamilton, Frank
影响因子：
6.8
作者：
AKAIKE, H
通讯作者：
AKAIKE, H
DOI：
10.1152/ajpgi.00023.2008
发表时间：
2008-06-01
影响因子：
4.5
作者：
Hasler, William L.;Coleski, Radoslav;Parkman, Henry P.
通讯作者：
Parkman, Henry P.