COVID-19 Associated Mucormycosis: A Systematic Review from Diagnostic Challenges to Management.
COVID-19 Associated Mucormycosis: A Systematic Review from Diagnostic Challenges to Management.
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DOI：
10.3390/diseases9040065
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发表时间：
2021-09-22
期刊：
影响因子：
--
通讯作者：
Ullah I
中科院分区：
文献类型：
--
作者：
Yasmin F;Najeeb H;Naeem A;Dapke K;Phadke R;Asghar MS;Shah SMI;De Berardis D;Ullah I
2019 年冠状病毒病 (COVID-19) 的爆发造成了重大破坏，在全球范围内夺去了超过 300 万人的生命。 SARS-COV-2 入侵后，高血糖和铁蛋白水平升高的免疫抑制以及类固醇治疗为机会性感染创造了完美风暴。越来越多的证据表明，COVID-19 患者在治疗期间或治疗后存在毛霉菌病合并感染。较差的预后、较晚的诊断以及与 COVID-19 相关的毛霉菌病的筛查和管理指南有限，使得医疗保健专业人员担心这种流行病会与大流行一起发生。本综述从地理角度报告了 COVID-19 相关毛霉菌病 (CAM) 病例，评估了 COVID-19 活动期或康复患者毛霉菌病的特征、临床表现和结果。它进一步描述了最佳管理疗法的预防策略和建议，这些策略和建议可以在全球范围内采用，以减少对医疗保健系统迫在眉睫的威胁。
The coronavirus disease 2019 (COVID-19) outbreak has caused significant destruction, claiming over three million lives worldwide. Post SARS-COV-2 invasion, immunosuppression with hyperglycemia and elevated ferritin levels along with steroidal treatment creates a perfect storm for opportunistic infections. There is increasing evidence of mucormycosis co-infection in COVID-19 patients, during or post-treatment. A worse prognosis, a late diagnosis, and limited guidelines of screening and management of COVID-19 associated mucormycosis have made healthcare professionals fear an epidemic alongside a pandemic. This review geographically reports cases of COVID-19 associated mucormycosis (CAM), evaluates characteristics, clinical manifestations, and outcomes of mucormycosis in COVID-19 active or recovered patients. It further describes preventive strategies and recommendations for optimal management therapy that can be adopted worldwide to curtail an impending threat to the healthcare system.
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DOI：
10.1056/nejmoa0901249
发表时间：
2009-08-27
期刊：
The New England journal of medicine
影响因子：
--
作者：
Fazel R;Krumholz HM;Wang Y;Ross JS;Chen J;Ting HH;Shah ND;Nasir K;Einstein AJ;Nallamothu BK
通讯作者：
Nallamothu BK
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin
影响因子：
1.7
作者：
Castrejón-Pérez AD;Welsh EC;Miranda I;Ocampo-Candiani J;Welsh O
通讯作者：
Welsh O
影响因子：
3.9
作者：
Falci, Diego R;Pasqualotto, Alessandro C
通讯作者：
Pasqualotto, Alessandro C
影响因子：
4.9
作者：
Bicanic, Tihana;Bottomley, Christian;Jarvis, Joseph N.
通讯作者：
Jarvis, Joseph N.