Inflammatory markers in population studies of aging.
Inflammatory markers in population studies of aging.
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DOI:
10.1016/j.arr.2010.11.002
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发表时间:
2011-07
影响因子:
13.1
通讯作者:
Newman, Anne B.
中科院分区:
文献类型:
--
作者:
Singh, Tushar;Newman, Anne B.
To review findings from major epidemiologic studies regarding risk factors and consequences of elevated markers of inflammation in older adults. Most of the large, current epidemiologic studies of older adults have included serum interleukin-6 (IL-6), C-reactive protein (CRP) and tumor necrosis factor alpha (TNF-alpha), and some more extensive batteries of measures including soluble receptors. Few risk factors for the modest elevations seen with aging have been defined, including, visceral adiposity, lower sex steroid hormones, smoking, and depression. Of the markers assessed, IL-6 is most robustly associated with disease, disability and mortality. IL-6 is a non-specific marker of adverse outcomes in older adults.
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DOI:
10.1056/nejmoa1000485
发表时间:
2010-07-08
期刊:
The New England journal of medicine
影响因子:
--
作者:
Basaria S;Coviello AD;Travison TG;Storer TW;Farwell WR;Jette AM;Eder R;Tennstedt S;Ulloor J;Zhang A;Choong K;Lakshman KM;Mazer NA;Miciek R;Krasnoff J;Elmi A;Knapp PE;Brooks B;Appleman E;Aggarwal S;Bhasin G;Hede-Brierley L;Bhatia A;Collins L;LeBrasseur N;Fiore LD;Bhasin S
通讯作者:
Bhasin S
影响因子:
37.8
作者:
Cushman, M;Arnold, AM;Tracy, RP
通讯作者:
Tracy, RP
影响因子:
5.8
作者:
Cesari, M.;Onder, G.;Zamboni, V.;Capoluongo, E.;Russo, A.;Bernabei, R.;Pahor, M.;Landi, F.
通讯作者:
Landi, F.
影响因子:
5.9
作者:
Cohen, HJ;Harris, T;Pieper, CF
通讯作者:
Pieper, CF
影响因子:
3.4
作者:
Beckett, N;Nunes, M;Bulpitt, C
通讯作者:
Bulpitt, C