Platelet factor 3 activity, platelet phospholipids and their fatty acid and aldehyde pattern in normal male subjects.

Platelet factor 3 activity, platelet phospholipids and their fatty acid and aldehyde pattern in normal male subjects.
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正常男性受试者的血小板因子 3 活性、血小板磷脂及其脂肪酸和醛模式。

DOI:
10.3109/00365516809167070
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发表时间:
1968
影响因子:
2.1
通讯作者:
S. Lund
S. Lund
中科院分区:
医学4区
文献类型:
--
作者:
A. Nordöy;S. Lund

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在Stypven系统中检测富含血小板血浆中的血小板因子3活性,并评价孵育时间、血小板数量以及ADP和高岭土的加入对其的影响。测定总脂、磷含量,并用薄层层析法进行磷脂分级。用气-液色谱分析了磷脂酰乙醇胺、磷脂酰丝氨酸、磷脂酰胆碱和鞘磷脂的脂肪酸和醛组成。在20名受试者中,观察到了血小板因子3活性以及各种磷脂的绝对和相对含量的一些变化。脂肪酸和醛的模式变化较大,但饱和和不饱和脂肪酸的比例保持不变,每种磷脂都表现出一种特征的脂肪酸模式。计算了血小板因子3活性与各磷脂组分的绝对量之间的相关系数。
The platelet factor 3 activity in platelet rich plasma was evaluated in a Stypven system and the influence of incubation time, platelet number and the addition of ADP and kaolin was estimated. The total lipid phosphorus content was measured and fractionation of the phospholipids was carried out by thin layer chromatography. The fatty acid and aldehyde composition of phosphatidyl ethanolamine, phosphatidyl serine, phosphatidyl choline and sphingomyelin was determined by gas liquid chromatography. Some variation in platelet factor 3 activity and in the absolute and relative content of the various phospholipids were observed within a group of 20 subjects. The fatty acid and aldehyde pattern showed more variation, however, the ratio between saturated and unsaturated fatty acids remained constant, and each of the phospholipids showed a characteristic fatty acid pattern. Correlation coefficients were calculated between platelet factor 3 activity and the absolute amount of the various phospholipid fractions and ...
DOI: --
发表时间: 1964-10
影响因子: 6.5
作者:
W. R. Morrison;L. Smith
通讯作者: W. R. Morrison;L. Smith