Interest in Long-Acting Injectable Pre-exposure Prophylaxis (LAI PrEP) Among Women in the Women's Interagency HIV Study (WIHS): A Qualitative Study Across Six Cities in the United States.
Interest in Long-Acting Injectable Pre-exposure Prophylaxis (LAI PrEP) Among Women in the Women's Interagency HIV Study (WIHS): A Qualitative Study Across Six Cities in the United States.
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DOI：
10.1007/s10461-020-03023-9
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发表时间：
2021-03
影响因子：
4.4
通讯作者：
Metsch LR
中科院分区：
文献类型：
--
作者：
Philbin MM;Parish C;Kinnard EN;Reed SE;Kerrigan D;Alcaide ML;Cohen MH;Sosanya O;Sheth AN;Adimora AA;Cocohoba J;Goparaju L;Golub ET;Fischl M;Metsch LR
长效注射（LAI）暴露前预防（PrEP）有可能促进依从性并改变艾滋病毒预防。然而，在面临独特障碍的女性中，很少有LAI PrEP研究。我们从2017年至2018年在妇女跨机构艾滋病毒研究的六个地点（纽约;芝加哥;旧金山弗朗西斯科;亚特兰大;华盛顿;查佩尔山）对30名艾滋病毒阴性妇女进行了深入采访。访谈记录，转录，并使用主题内容分析进行分析。很少有女性表示对PrEP感兴趣，当被提示选择一种方案时，55%的人更喜欢LAI，10%的人每天服用药丸，33%的人表示无论配方如何，他们都不会服用PrEP。感知的障碍包括：1）对新的和感知的未经测试的注射产品的恐惧和2）潜在的副作用（例如，注射部位疼痛、恶心）。促进因素包括：1）相信注射比药片更有效; 2）方便和方便; 3）保密。未来的研究应纳入妇女的LAI PrEP相关经验，以促进吸收。
Long-acting injectable (LAI) pre-exposure prophylaxis (PrEP) has the potential to facilitate adherence and transform HIV prevention. However, little LAI PrEP research has occurred among women, who face unique barriers. We conducted 30 in-depth interviews with HIV-negative women from 2017–2018 across six sites (New York; Chicago; San Francisco; Atlanta; Washington, DC; Chapel Hill) of the Women’s Interagency HIV Study. Interviews were recorded, transcribed, and analyzed using thematic content analysis. Few women expressed interest in PrEP and when prompted to choose a regimen, 55% would prefer LAI, 10% daily pills, and 33% said they would not take PrEP regardless of formulation. Perceived barriers included: 1) the fear of new—and perceived untested—injectable products and 2) potential side effects (e.g., injection-site pain, nausea). Facilitators included: 1) Believing shots were more effective than pills; 2) ease and convenience; and 3) confidentiality. Future studies should incorporate women’s LAI PrEP-related experiences to facilitate uptake.
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影响因子：
1.5
作者：
Beaulaurier, Richard;Fortuna, Karen;Emlet, Charles A.
通讯作者：
Emlet, Charles A.
影响因子：
1.3
作者：
Coleman, Christopher Lance
通讯作者：
Coleman, Christopher Lance
影响因子：
4.4
作者：
Carter, Allison;Roth, Eric Abella;Kaida, Angela
通讯作者：
Kaida, Angela
影响因子：
1.7
作者：
Cahill S;Taylor SW;Elsesser SA;Mena L;Hickson D;Mayer KH
通讯作者：
Mayer KH
DOI：
10.1097/qai.0000000000001165
发表时间：
2017-01-01
期刊：
Journal of acquired immune deficiency syndromes (1999)
影响因子：
--
作者：
Elopre L;Kudroff K;Westfall AO;Overton ET;Mugavero MJ
通讯作者：
Mugavero MJ