Epithelial expression and role of secreted STC1 on asthma airway hyperresponsiveness through calcium channel modulation

Epithelial expression and role of secreted STC1 on asthma airway hyperresponsiveness through calcium channel modulation
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上皮表达及分泌型 STC1 通过钙通道调节对哮喘气道高反应性的作用

DOI:
10.1111/all.14727
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发表时间:
2020-12
期刊:
影响因子:
12.4
通讯作者:
Yao Xin
Yao Xin
中科院分区:
医学1区
文献类型:
--
作者:
Xu Jiayan;Meng Yaqi;Jia Man;Jiang Jie;Yang Yi;Ou Yingwei;Wu Yunhui;Yan Xiaoyi;Huang Mao;Adcock Ian M.;Yao Xin

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哮喘的特征是呼吸道高反应性(AHR)、炎症和气道重塑。气道高反应性是由上皮源性松弛因子控制下的气道平滑肌收缩增强所致。
Asthma is characterized by airway hyperresponsiveness (AHR), inflammation, and airway remodeling. Airway hyperresponsiveness results from enhanced airway smooth muscle (ASM) contraction potentially under the control of an epithelium‐derived relaxing facto
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