Engineered chimeric antigen receptor-expressing T cells for the treatment of pancreatic ductal adenocarcinoma.
Engineered chimeric antigen receptor-expressing T cells for the treatment of pancreatic ductal adenocarcinoma.
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设计的嵌合抗原受体T细胞用于治疗胰腺导管腺癌。
DOI:
10.4161/onci.28327
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发表时间:
2014
期刊:
影响因子:
7.2
通讯作者:
Beatty GL
中科院分区:
文献类型:
--
作者:
Beatty GL
Adoptive cell therapy with chimeric antigen receptor (CAR)-engineered T cells is under investigation as an approach to restore productive T cell immunosurveillance in patients with pancreatic ductal adenocarcinoma. Early findings demonstrate safety of this cell-based therapy and the capacity of CAR-expressing T cells to mediate anti-tumor activity as well as induce endogeneous antitumoral immune responses.
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DOI:
10.1056/nejmoa1003466
发表时间:
2010-08-19
期刊:
The New England journal of medicine
影响因子:
--
作者:
Hodi FS;O'Day SJ;McDermott DF;Weber RW;Sosman JA;Haanen JB;Gonzalez R;Robert C;Schadendorf D;Hassel JC;Akerley W;van den Eertwegh AJ;Lutzky J;Lorigan P;Vaubel JM;Linette GP;Hogg D;Ottensmeier CH;Lebbé C;Peschel C;Quirt I;Clark JI;Wolchok JD;Weber JS;Tian J;Yellin MJ;Nichol GM;Hoos A;Urba WJ
通讯作者:
Urba WJ
影响因子:
32.4
作者:
Kalos M;June CH
通讯作者:
June CH
DOI:
10.1084/jem.20031435
发表时间:
2004-08-02
期刊:
The Journal of experimental medicine
影响因子:
--
作者:
Thomas AM;Santarsiero LM;Lutz ER;Armstrong TD;Chen YC;Huang LQ;Laheru DA;Goggins M;Hruban RH;Jaffee EM
通讯作者:
Jaffee EM
DOI:
10.1056/nejmoa1200694
发表时间:
2012-06-28
期刊:
The New England journal of medicine
影响因子:
--
作者:
Brahmer JR;Tykodi SS;Chow LQ;Hwu WJ;Topalian SL;Hwu P;Drake CG;Camacho LH;Kauh J;Odunsi K;Pitot HC;Hamid O;Bhatia S;Martins R;Eaton K;Chen S;Salay TM;Alaparthy S;Grosso JF;Korman AJ;Parker SM;Agrawal S;Goldberg SM;Pardoll DM;Gupta A;Wigginton JM
通讯作者:
Wigginton JM
影响因子:
11.2
作者:
Zhao Y;Moon E;Carpenito C;Paulos CM;Liu X;Brennan AL;Chew A;Carroll RG;Scholler J;Levine BL;Albelda SM;June CH
通讯作者:
June CH