Three-dimensional periodic supramolecular organic framework ion sponge in water and microcrystals.
Three-dimensional periodic supramolecular organic framework ion sponge in water and microcrystals.
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水和微晶中三维周期性超分子有机骨架离子海绵
DOI：
10.1038/ncomms6574
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发表时间：
2014-12-03
影响因子：
16.6
通讯作者：
Li, Zhan-Ting
中科院分区：
文献类型：
--
作者：
Tian, Jia;Zhou, Tian-You;Zhang, Shao-Chen;Aloni, Shaul;Altoe, Maria Virginia;Xie, Song-Hai;Wang, Hui;Zhang, Dan-Wei;Zhao, Xin;Liu, Yi;Li, Zhan-Ting
自组装已成为生成复杂超分子结构的有效方法。尽管报道了许多固态晶体框架，但在三维空间中构建高度可溶的周期性超分子网络仍然是一个挑战。在这里，我们证明了封装基序涉及葫芦[8]脲内两个芳香单元的二聚，可用于指导四位分子块和葫芦[8]脲在水中共组装成周期性三维超分子有机框架。溶液相小角度 X 射线散射和衍射实验支持超分子有机骨架的周期性。蒸发溶剂后，多孔微晶中保持了骨架的周期性。作为超分子“离子海绵”，该框架可以吸附水和微晶中的不同种类的阴离子客体，包括药物，并且微晶中吸附的药物可以选择性地释放到水中。
Self-assembly has emerged as a powerful approach to generating complex supramolecular architectures. Despite there being many crystalline frameworks reported in the solid state, the construction of highly soluble periodic supramolecular networks in a three-dimensional space is still a challenge. Here we demonstrate that the encapsulation motif, which involves the dimerization of two aromatic units within cucurbit[8]uril, can be used to direct the co-assembly of a tetratopic molecular block and cucurbit[8]uril into a periodic three-dimensional supramolecular organic framework in water. The periodicity of the supramolecular organic framework is supported by solution-phase small-angle X-ray-scattering and diffraction experiments. Upon evaporating the solvent, the periodicity of the framework is maintained in porous microcrystals. As a supramolecular ‘ion sponge’, the framework can absorb different kinds of anionic guests, including drugs, in both water and microcrystals, and drugs absorbed in microcrystals can be released to water with selectivity.
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影响因子：
56.9
作者：
Côté, AP;Benin, AI;Yaghi, OM
通讯作者：
Yaghi, OM
影响因子：
64.8
作者：
Cordier, Philippe;Tournilhac, Francois;Leibler, Ludwik
通讯作者：
Leibler, Ludwik
DOI：
10.1073/pnas.97.23.12418
发表时间：
2000-11-07
影响因子：
11.1
作者：
Castellano, RK;Clark, R;Rebek, J
通讯作者：
Rebek, J
影响因子：
15
作者：
Desiraju, Gautain R.
通讯作者：
Desiraju, Gautain R.
DOI：
10.1126/science.1205962
发表时间：
2012-02-17
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Aida T;Meijer EW;Stupp SI
通讯作者：
Stupp SI