MicroRNAs in lung cancer.
MicroRNAs in lung cancer.
复制标题
DOI:
10.18632/oncotarget.20955
复制
发表时间:
2017-10-06
期刊:
影响因子:
--
通讯作者:
De Mello RA
中科院分区:
文献类型:
--
作者:
Castro D;Moreira M;Gouveia AM;Pozza DH;De Mello RA
Lung cancer (LC) is a serious public health problem responsible for the majority of cancer deaths and comorbidities in developed countries. Tobacco smoking is considered the main risk factor for LC; however, only a few smokers will be affected by this cancer. Current screening methods are focused on identifying the early stages of this malignancy. Thus, new data concerning the roles of microRNA alterations in inflammation, epithelial-mesenchymal transition and lung disease have increased hope about LC pathogenesis, diagnosis, treatment and prognosis. MicroRNA mechanisms include angiogenesis promotion, cell cycle regulation by modulating cellular proliferation and apoptosis, and migration and invasion inhibition. In this context, this manuscript reviews the current information about many important microRNAs as they relate to the initiation and progression of LC.
登录
查看更多内容
影响因子:
3.2
作者:
Su K;Zhang T;Wang Y;Hao G
通讯作者:
Hao G
影响因子:
8
作者:
Shi ZM;Wang L;Shen H;Jiang CF;Ge X;Li DM;Wen YY;Sun HR;Pan MH;Li W;Shu YQ;Liu LZ;Peiper SC;He J;Jiang BH
通讯作者:
Jiang BH
影响因子:
4.4
作者:
Halappanavar, Sabina;Nikota, Jake;Stampfli, Martin
通讯作者:
Stampfli, Martin
影响因子:
4.8
作者:
Izzotti, Alberto;Calin, George A.;De Flora, Silvio
通讯作者:
De Flora, Silvio
DOI:
10.1016/j.bbrc.2014.11.093
发表时间:
2015-01-02
影响因子:
3.1
作者:
Shan, Nianxi;Shen, Liangfang;Duan, Chaojun
通讯作者:
Duan, Chaojun