Stringent Response Regulates Stress Resistance in Cyanobacterium Microcystis aeruginosa.
Stringent Response Regulates Stress Resistance in Cyanobacterium Microcystis aeruginosa.
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DOI：
10.3389/fmicb.2020.511801
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发表时间：
2020
影响因子：
5.2
通讯作者：
Cai ZH
中科院分区：
文献类型：
--
作者：
Jin H;Lao YM;Ying KZ;Zhou J;Cai ZH
蓝藻繁殖是全球淡水生态系统中严重的环境问题。氮限制是控制蓝藻华最重要的策略之一。但近年来的研究表明，限氮不能有效地控制花华；相反，氮限制诱导固氮蓝藻华。这一生态事件背后的机制尚不清楚。在本研究中，我们发现氮限制通过触发严格反应（SR）来增强铜绿微囊藻的抗逆性，SR是细菌对环境胁迫最重要的适应性反应之一。SR启动通过促进菌落形成、维持膜完整性、提高光合性能、减少ROS产生、上调胁迫相关基因等方式对细胞进行盐胁迫和氧化胁迫保护。这些保护措施可能有助于铜绿假单胞菌在季节性氮素限制期间保持其种群数量。由于SR已被证实在氮限制条件下参与固氮，因此本文讨论了SR在推动蓝藻华转移和演替中的潜在作用。我们的发现提供了细胞证据和可能的机制，减少氮输入对控制开花无效。
Cyanobacterial blooms are serious environmental issues in global freshwater ecosystems. Nitrogen limitation is one of the most important strategies to control cyanobacterial blooms. However, recent researches showed that N limitation does not effectively control the bloom; oppositely, N limitation induces N-fixing cyanobacterial blooms. The mechanism underlying this ecological event is elusive. In this study, we found that N limitation enhances stress tolerance of Microcystis aeruginosa by triggering stringent response (SR), one of the most important bacterial adaptive responses to environmental stresses. Initiation of SR exerted protective effects on the cells against salt and oxidative stresses by promoting colony formation, maintaining membrane integrity, increasing photosynthetic performance, reducing ROS production, upregulating stress-related genes, etc. These protections possibly help M. aeruginosa maintain their population number during seasonal N limitation. As SR has been proven to be involved in nitrogen fixing under N limitation conditions, the potential role of SR in driving the shift and succession of cyanobacterial blooms was discussed. Our findings provide cellular evidence and possible mechanisms that reducing N input is ineffective for bloom control.
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影响因子：
3.7
作者：
Atkinson GC;Tenson T;Hauryliuk V
通讯作者：
Hauryliuk V
影响因子：
9.2
作者：
Klotz, Alexander;Georg, Jens;Forchhammer, Karl
通讯作者：
Forchhammer, Karl
影响因子：
3.5
作者：
AKINYANJU, J;SMITH, RJ
通讯作者：
SMITH, RJ
DOI：
10.1007/978-0-387-75865-7_33
发表时间：
2008-01-01
期刊：
CYANOBACTERIAL HARMFUL ALGAL BLOOMS: STATE OF THE SCIENCE AND RESEARCH NEEDS
影响因子：
--
作者：
Havens, Karl E.
通讯作者：
Havens, Karl E.
影响因子：
10.5
作者：
Harris, BZ;Kaiser, D;Singer, M
通讯作者：
Singer, M