Earlier Resolution of Symptoms and Return of Function After Bridge-Enhanced Anterior Cruciate Ligament Repair As Compared With Anterior Cruciate Ligament Reconstruction.
Earlier Resolution of Symptoms and Return of Function After Bridge-Enhanced Anterior Cruciate Ligament Repair As Compared With Anterior Cruciate Ligament Reconstruction.
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DOI：
10.1177/23259671211052530
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发表时间：
2021-11
影响因子：
2.6
通讯作者：
Micheli LJ
中科院分区：
文献类型：
--
作者：
Barnett SC;Murray MM;Badger GJ;BEAR Trial Team;Yen YM;Kramer DE;Sanborn R;Kiapour A;Proffen B;Sant N;Fleming BC;Micheli LJ
与自体移植前交叉韧带重建（ACLR）相比，桥增强前交叉韧带修复（BEAR）在2年内具有良好的患者报告结果。然而，BEAR和自体移植ACLR在早期时间点的比较——包括膝关节疼痛和症状的缓解、力量恢复和恢复运动等重要结果——尚未报道。假设BEAR组在国际膝关节文献委员会和膝关节损伤和骨关节炎结局评分中有更高的结果，以及术后早期肌肉力量的改善。随机对照试验；证据等级：1。共有100例年龄在13至35岁之间的完全前交叉韧带中间物质损伤患者被随机分为两组，分别接受细胞外基质植入（n = 65）和自体ACLR移植（n = 35）。结果在术后2年的时间点进行评估。混合模型重复测量分析用于比较BEAR和ACLR的结果。患者在随访2年后恢复失明。重复测量测试显示，组对国际膝关节文献委员会主观评分有显著影响（P = 0.015），在手术后6个月最明显（BEAR = 86分对ACLR = 78分；P = 0.001）。组对膝关节损伤和骨关节炎结局评分-症状亚量表评分有显著影响（P = 0.010），主要归因于术后1年时间点BEAR评分较高（88比82；P = 0.009）。在重复测量分析中，组对腘绳肌力量的影响是显著的（P < .001），在所有术后时间点（P < .001）。术后1年，BEAR组约88%的患者和ACLR组76%的患者恢复运动（P = 0.261）。在2年的随访期间，接受BEAR手术的患者症状得到早期缓解，对膝关节功能的满意度提高，腘绳肌力量也得到改善。NCT02664545 （ClinicalTrials.gov标识符）
Bridge-enhanced anterior cruciate ligament repair (BEAR) has noninferior patient-reported outcomes when compared with autograft anterior cruciate ligament reconstruction (ACLR) at 2 years. However, the comparison of BEAR and autograft ACLR at earlier time points—including important outcomes such as resolution of knee pain and symptoms, recovery of strength, and return to sport—has not yet been reported. It was hypothesized that the BEAR group would have higher outcomes on the International Knee Documentation Committee and Knee injury and Osteoarthritis Outcome Score, as well as improved muscle strength, in the early postoperative period. Randomized controlled trial; Level of evidence, 1. A total of 100 patients aged 13 to 35 years with complete midsubstance anterior cruciate ligament injuries were randomized to receive a suture repair augmented with an extracellular matrix implant (n = 65) or an autograft ACLR (n = 35). Outcomes were assessed at time points up to 2 years postoperatively. Mixed-model repeated-measures analyses were used to compare BEAR and ACLR outcomes. Patients were unblinded after their 2-year visit. Repeated-measures testing revealed a significant effect of group on the International Knee Documentation Committee Subjective Score (P = .015), most pronounced at 6 months after surgery (BEAR = 86 points vs ACLR = 78 points; P = .001). There was a significant effect of group on the Knee injury and Osteoarthritis Outcome Score-Symptoms subscale scores (P = .010), largely attributed to the higher BEAR scores at the 1-year postoperative time point (88 vs 82; P = .009). The effect of group on hamstring strength was significant in the repeated-measures analysis (P < .001), as well as at all postoperative time points (P < .001 for all comparisons). At 1 year after surgery, approximately 88% of the patients in the BEAR group and 76% of the ACLR group had been cleared for return to sport (P = .261). Patients undergoing the BEAR procedure had earlier resolution of symptoms and increased satisfaction about their knee function, as well as improved resolution of hamstring muscle strength throughout the 2-year follow-up period. NCT02664545 (ClinicalTrials.gov identifier)
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股四头肌强度对称性不会在前交叉韧带重建，康复和重返运动训练后修改步态力学。
DOI：
10.1177/0363546520980079
发表时间：
2021-03
期刊：
The American journal of sports medicine
影响因子：
--
作者：
Arhos EK;Capin JJ;Buchanan TS;Snyder-Mackler L
通讯作者：
Snyder-Mackler L
DOI：
10.2106/00004623-198870100-00007
发表时间：
1988-12-01
影响因子：
5.3
作者：
CLANCY, WG;RAY, JM;ZOLTAN, DJ
通讯作者：
ZOLTAN, DJ
DOI：
10.2106/00004623-200112000-00014
发表时间：
2001-12-01
影响因子：
5.3
作者：
Lingard, EA;Katz, JN;Sledge, CB
通讯作者：
Sledge, CB
影响因子：
3.3
作者：
Kaeding CC;Aros B;Pedroza A;Pifel E;Amendola A;Andrish JT;Dunn WR;Marx RG;McCarty EC;Parker RD;Wright RW;Spindler KP
通讯作者：
Spindler KP
DOI：
10.2174/1874325001206010231
发表时间：
2012
期刊：
The open orthopaedics journal
影响因子：
--
作者：
Magarian EM;Vavken P;Connolly SA;Mastrangelo AN;Murray MM
通讯作者：
Murray MM