NEMA NU 2-2007 performance measurements of the Siemens Inveon preclinical small animal PET system.
NEMA NU 2-2007 performance measurements of the Siemens Inveon preclinical small animal PET system.
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DOI：
10.1088/0031-9155/54/8/007
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发表时间：
2009-04-21
影响因子：
3.5
通讯作者：
Lowe VJ
中科院分区：
文献类型：
--
作者：
Kemp BJ;Hruska CB;McFarland AR;Lenox MW;Lowe VJ
美国电气制造商协会 (NEMA) NU 2-2007 性能测量是在西门子医疗解决方案公司开发的 Inveon™ 临床前小动物 PET 系统上进行的。扫描仪使用 1.51 × 1.51 × 10 mm LSO 晶体，分为 20 × 20 块；锥形光导将 LSO 晶体块与位置敏感光电倍增管耦合。共有 80 枚戒指，每枚戒指 320 颗水晶，戒指直径为 161 毫米。横轴和轴向视场 (FOV) 分别为 100 毫米和 127 毫米。扫描仪可与 CT 扫描仪对接； CT组件的性能特征不包括在本文中。对于不同的能量窗口和符合定时窗口宽度，获得了空间分辨率、灵敏度、散射分数和计数率性能的性能测量。为简洁起见，此处描述的结果适用于 350-650 keV 的能量窗口和 3.43 ns 的重合时间窗口。横轴和轴向FOV中心的空间分辨率在切向、径向和轴向方向上分别为1.56、1.62和2.12 mm，线源的系统灵敏度为36.2 cps kBq−1（点源为7.2%）。对于小鼠和大鼠大小的模型，散射分数分别为 5.7% 和 14.6%。对于小鼠大小的体模，噪声随机估计的峰值噪声等效计数率为 130 MBq 时的 1475 kcps，对于大鼠大小的体模而言，峰值噪声等效计数率为 74 MBq 时的 583 kcps。性能测量表明，Inveon™ PET 扫描仪是一款高分辨率断层扫描仪，具有出色的灵敏度，能够以高计数率成像。
National Electrical Manufacturers Association (NEMA) NU 2-2007 performance measurements were conducted on the Inveon™ preclinical small animal PET system developed by Siemens Medical Solutions. The scanner uses 1.51 × 1.51 × 10 mm LSO crystals grouped in 20 × 20 blocks; a tapered light guide couples the LSO crystals of a block to a position-sensitive photomultiplier tube. There are 80 rings with 320 crystals per ring and the ring diameter is 161 mm. The transaxial and axial fields of view (FOVs) are 100 and 127 mm, respectively. The scanner can be docked to a CT scanner; the performance characteristics of the CT component are not included herein. Performance measurements of spatial resolution, sensitivity, scatter fraction and count rate performance were obtained for different energy windows and coincidence timing window widths. For brevity, the results described here are for an energy window of 350–650 keV and a coincidence timing window of 3.43 ns. The spatial resolution at the center of the transaxial and axial FOVs was 1.56, 1.62 and 2.12 mm in the tangential, radial and axial directions, respectively, and the system sensitivity was 36.2 cps kBq−1 for a line source (7.2% for a point source). For mouse- and rat-sized phantoms, the scatter fraction was 5.7% and 14.6%, respectively. The peak noise equivalent count rate with a noisy randoms estimate was 1475 kcps at 130 MBq for the mouse-sized phantom and 583 kcps at 74 MBq for the rat-sized phantom. The performance measurements indicate that the Inveon™ PET scanner is a high-resolution tomograph with excellent sensitivity that is capable of imaging at a high count rate.
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影响因子：
3.8
作者：
Funk, T;Sun, MS;Hasegawa, BH
通讯作者：
Hasegawa, BH
影响因子：
1.8
作者：
Cherry, SR;Shao, Y;Phelps, ME
通讯作者：
Phelps, ME
影响因子：
1.8
作者：
LECOMTE, R;CADORETTE, J;ROULEAU, D
通讯作者：
ROULEAU, D
DOI：
10.1007/s002590050211
发表时间：
1998-02-01
期刊：
EUROPEAN JOURNAL OF NUCLEAR MEDICINE
影响因子：
--
作者：
Hume, SP;Gunn, RN;Jones, T
通讯作者：
Jones, T
影响因子：
9.3
作者：
Goertzen, Andrew L.;Suk, Joon Young;Thompson, Christopher J.
通讯作者：
Thompson, Christopher J.