A large-scale LC-MS dataset of murine liver proteome from time course of heavy water metabolic labeling.
A large-scale LC-MS dataset of murine liver proteome from time course of heavy water metabolic labeling.
复制标题
DOI:
10.1038/s41597-023-02537-w
复制
发表时间:
2023-09-19
期刊:
影响因子:
9.8
通讯作者:
Sadygov, Rovshan G.
中科院分区:
文献类型:
--
作者:
Deberneh, Henock M.;Abdelrahman, Doaa R.;Verma, Sunil K.;Linares, Jennifer J.;Murton, Andrew J.;Russell, William K.;Kuyumcu-Martinez, Muge N.;Miller, Benjamin F.;Sadygov, Rovshan G.
Metabolic stable isotope labeling with heavy water followed by liquid chromatography coupled with mass spectrometry (LC-MS) is a powerful tool for in vivo protein turnover studies. Several algorithms and tools have been developed to determine the turnover rates of peptides and proteins from time-course stable isotope labeling experiments. The availability of benchmark mass spectrometry data is crucial to compare and validate the effectiveness of newly developed techniques and algorithms. In this work, we report a heavy water-labeled LC-MS dataset from the murine liver for protein turnover rate analysis. The dataset contains eighteen mass spectral data with their corresponding database search results from nine different labeling durations and quantification outputs from d2ome+ software. The dataset also contains eight mass spectral data from two-dimensional fractionation experiments on unlabeled samples.
登录
查看更多内容
影响因子:
4.4
作者:
Sadygov VR;Zhang W;Sadygov RG
通讯作者:
Sadygov RG
DOI:
10.1016/j.bbagen.2005.12.023
发表时间:
2006-05-01
影响因子:
3
作者:
Busch, Robert;Kim, Yoo-Kyeong;Hellerstein, Marc K.
通讯作者:
Hellerstein, Marc K.
影响因子:
5.6
作者:
通讯作者:
--
影响因子:
5.6
作者:
Sadygov RG
通讯作者:
Sadygov RG
影响因子:
7.4
作者:
Sadygov, Rovshan G.;Maroto, Fernando Martin;Huehmer, Andreas F. R.
通讯作者:
Huehmer, Andreas F. R.