Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT).
Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT).
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DOI：
10.1007/s10865-012-9473-6
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发表时间：
2014-04
影响因子：
3.1
通讯作者：
Kip, Kevin E.
中科院分区：
文献类型：
--
作者：
Lengacher, Cecile A.;Shelton, Melissa M.;Reich, Richard R.;Barta, Michelle K.;Johnson-Mallard, Versie;Moscoso, Manolete S.;Paterson, Carly;Ramesar, Sophia;Budhrani, Pinky;Carranza, Irina;Lucas, Jean;Jacobsen, Paul B.;Goodman, Matthew J.;Kip, Kevin E.
探讨MBSR（BC）的作用机制，包括减少对复发的恐惧和其他潜在的介质。82名治疗后乳腺癌幸存者（0-III期）被随机分配到为期6周的MBSR（BC）计划（n=40）或常规护理组（n=42）。在基线和6周时评估心理和生理变量作为潜在的调节因素。与UC相比，MBSR（BC）在5个潜在介质上发生了有利的变化：(i)对问题复发的恐惧的改变介导了MBSR（BC）对6周感知压力（z=2.12, p=0.03）和状态焦虑（z=2.03, p=0.04）的影响；（ii）生理功能的改变介导MBSR（BC）对感知压力（z=2.27, p=0.02）和特质焦虑（z=1.98, p=0.05） 6周变化的影响。正念减压疗法（BC）减少对复发的恐惧，改善身体机能，从而减少感知到的压力和焦虑。研究结果支持正念减压（BC）的有益作用，并为可能的认知机制提供了见解。
To investigate the mechanism(s) of action of MBSR(BC) including reductions in fear of recurrence and other potential mediators. Eighty-two post-treatment breast cancer survivors (stages 0-III) were randomly assigned to a 6-week MBSR(BC) program (n=40) or to Usual Care group (UC) (n=42). Psychological and physical variables were assessed as potential mediators at baseline and at 6 weeks. MBSR(BC) compared to UC experienced favorable changes for five potential mediators: (i) change in fear of recurrence problems mediated the effect of MBSR(BC) on 6-week change in perceived stress (z=2.12, p=0.03) and state anxiety (z=2.03, p=0.04); and (ii) change in physical functioning mediated the effect of MBSR(BC) on 6-week change in perceived stress (z=2.27, p=0.02) and trait anxiety (z=1.98, p=0.05). MBSR(BC) reduces fear of recurrence and improves physical functioning which reduces perceived stress and anxiety. Findings support the beneficial effects of MBSR(BC) and provide insight into the possible cognitive mechanism of action.
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影响因子：
7.6
作者：
BARON, RM;KENNY, DA
通讯作者：
KENNY, DA
影响因子：
5
作者：
COHEN, S;KAMARCK, T;MERMELSTEIN, R
通讯作者：
MERMELSTEIN, R
影响因子：
45.3
作者：
Armes, Jo;Crowe, Maggie;Richardson, Alison
通讯作者：
Richardson, Alison
DOI：
10.1111/j.1467-842x.2000.tb00137.x
发表时间：
2000-04-01
影响因子：
3.5
作者：
Girgis, A;Boyes, A;Burrows, S
通讯作者：
Burrows, S
适应治疗后的生活：治疗乳腺癌后生活质量和生活质量。
影响因子：
8.8
作者：
Costanzo, E. S.;Lutgendorf, S. K.;Mattes, M. L.;Trehan, S.;Robinson, C. B.;Tewfik, F.;Roman, S. L.
通讯作者：
Roman, S. L.