Adjusting to life after treatment: distress and quality of life following treatment for breast cancer.
Adjusting to life after treatment: distress and quality of life following treatment for breast cancer.
复制标题
适应治疗后的生活：治疗乳腺癌后生活质量和生活质量。
DOI：
10.1038/sj.bjc.6604091
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发表时间：
2007-12-17
影响因子：
8.8
通讯作者：
Roman, S. L.
中科院分区：
文献类型：
--
作者：
Costanzo, E. S.;Lutgendorf, S. K.;Mattes, M. L.;Trehan, S.;Robinson, C. B.;Tewfik, F.;Roman, S. L.
临床和轶事研究结果表明，癌症治疗的完成可能以高度的痛苦和中断的调整为标志。本研究探讨了在3个月的心理调整治疗后的89名妇女0-III期乳腺癌。参与者在三个时间点完成了抑郁，癌症相关焦虑，癌症担忧和生活质量的测量：治疗期间，治疗结束后3周和治疗后3个月。治疗后评分提示大多数妇女心理适应良好。此外，治疗后的痛苦并没有增加;纵向分析显示，抑郁或复发的担忧没有显着变化，而侵入性思维减少，生活质量提高。年轻的年龄预测更大的痛苦的措施。抑郁或焦虑史预示着更大的抑郁症，而更广泛的治疗预示着更大的癌症相关焦虑。尽管缺乏对一般抑郁和焦虑指数的支持，但参与者报告了与癌症相关的担忧相关的中度痛苦，包括身体问题，对癌症复发的恐惧和恢复正常生活。总而言之，虽然乳腺癌幸存者在治疗后对一般痛苦指数进行了良好的调整，但一些女性仍有持续痛苦的风险。此外，与癌症相关的重大问题普遍存在，可能是重要的干预目标。
Clinical and anecdotal findings suggest that the completion of cancer treatment may be marked by heightened distress and disrupted adjustment. The present study examined psychological adjustment during the 3 months following treatment among 89 women with stages 0–III breast cancer. Participants completed measures of depression, cancer-related anxiety, cancer concerns, and quality of life at three time points: during treatment, 3 weeks following the end of treatment, and 3 months post-treatment. Post-treatment scores were suggestive of good psychological adjustment among the majority of women. Moreover, distress did not increase following treatment; longitudinal analyses showed no significant changes in depression or recurrence worry, while intrusive thoughts decreased, and quality of life improved. Younger age predicted greater distress across measures. A history of depression or anxiety predicted greater depressive symptomatology, while more extensive treatment predicted greater cancer-related anxiety. Despite the lack of distress endorsed on general depression and anxiety indices, participants reported moderate distress associated with cancer-related concerns, including physical problems, fear of cancer recurrence, and resuming normal life. In sum, while breast cancer survivors demonstrate good adjustment on general distress indices following treatment, some women are at risk for sustained distress. Moreover, significant cancer-related concerns are prevalent and may be important intervention targets.
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影响因子：
45.3
作者：
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通讯作者：
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