Antibiofilm polysaccharides.
Antibiofilm polysaccharides.
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DOI:
10.1111/j.1462-2920.2012.02810.x
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发表时间:
2013-02
影响因子:
5.1
通讯作者:
Ghigo JM
中科院分区:
文献类型:
--
作者:
Rendueles O;Kaplan JB;Ghigo JM
Bacterial extracellular polysaccharides have been shown to mediate many of the cell-to cell and cell-to-surface interactions that are required for the formation, cohesion and stabilization of bacterial biofilms. However, recent studies have identified several bacterial polysaccharides that inhibit biofilm formation by a wide-spectrum of bacteria and fungi both in vitro and in vivo. This review discusses the composition, modes of action, and potential biological roles of antibiofilm polysaccharides recently identified in bacteria and eukaria. Some of these molecules may have technological applications as antibiofilm agents in industry and medicine.
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