Early physical rehabilitation effectiveness in frail older patients hospitalized for community-acquired pneumonia: analysis of a nationwide database in Japan
Early physical rehabilitation effectiveness in frail older patients hospitalized for community-acquired pneumonia: analysis of a nationwide database in Japan
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因社区获得性肺炎住院的体弱老年患者的早期物理康复效果：对日本全国数据库的分析
DOI：
10.1007/s40520-022-02302-w
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发表时间：
2022
影响因子：
4
通讯作者：
Momosaki Ryo
中科院分区：
文献类型：
--
作者：
Shimizu Akio;Maeda Keisuke;Inoue Tatsuro;Mori Naoharu;Momosaki Ryo
脆弱是预测老年社区获得性肺炎(CAP)患者预后的重要指标。目的探讨早期康复干预是否能有效减少因慢性前列腺炎住院的老年虚弱患者的不良反应。方法对2014年至2020年日本诊断程序组合数据库中登记的65岁 ≥ 老年慢性萎缩性胃炎患者进行回顾性队列分析。我们比较了入院后3天内接受和未接受身体康复治疗的患者的30天死亡率和再住院率，并使用COX回归模型和反向概率加权进行敏感性分析，评估了早期接受身体康复治疗与预后之间的关系。结果共纳入31,133名因慢性前列腺炎住院的虚弱老年患者(平均年龄84.3 ± 6.3岁；女性，49.1%)，其中11,515人(37.0%)接受了早期身体康复治疗。Cox回归分析显示，早期身体康复干预与30天死亡率和再住院率呈负相关。IPW模型也显示了类似的结果。讨论早期身体康复与虚弱的老年CAP患者30天死亡率、住院总死亡率和30天再住院率的风险降低相关。结论虚弱的老年CAP患者住院期间早期身体康复可能会改善预后。这一发现强调了在临床实践中同时引入HFRS和早期物理康复干预对虚弱的老年CAP患者的重要性。
BackgroundFrailty is a significant predictor of prognosis in older patients with community-acquired pneumonia (CAP). No effective therapy has been reported in frail patients with CAP, with frailty determined using the Hospital Frailty Risk Score (HFRS).AimsTo investigate whether early physical rehabilitation intervention would effectively minimize adverse outcomes in frail older patients (determined using the HFRS) hospitalized for CAP.MethodsThis retrospective cohort analysis involved patients with CAP aged ≥ 65 years enrolled in the Japanese Diagnostic Procedure Combination Database between 2014 and 2020 and assessed as being frail. We compared 30-day mortality and readmission rates for patients who did and who did not receive physical rehabilitation within three days of admission and evaluated the association between outcomes and receiving early physical rehabilitation using Cox regression models and inverse probability weighting (IPW) for sensitivity analysis.ResultsThe analysis involved 31,133 frail older patients hospitalized for CAP (mean age 84.3 ± 6.3 years; females, 49.1%), including 11,515 (37.0%) who received early physical rehabilitation. Cox regression analysis showed that early physical rehabilitation intervention was inversely associated with 30-day mortality and readmission rates. The IPW model also showed similar results.DiscussionEarly physical rehabilitation was associated with reduced risks of 30-day mortality, overall in-hospital mortality, and 30-day readmission rates in frail older patients with CAP.ConclusionsEarly physical rehabilitation in frail older patients hospitalized for CAP may improve outcomes. This finding highlights the importance of simultaneously introducing the HFRS and early physical rehabilitation intervention into clinical practice for frail older patients with CAP.
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影响因子：
5.9
作者：
Shimizu A;Fujishima I;Maeda K;Wakabayashi H;Nishioka S;Ohno T;Nomoto A;Kayashita J;Mori N;The Japanese Working Group On Sarcopenic Dysphagia
通讯作者：
The Japanese Working Group On Sarcopenic Dysphagia
DOI：
10.1016/j.jinf.2020.09.029
发表时间：
2020-12
期刊：
The Journal of infection
影响因子：
--
作者：
Kundi H;Çetin EHÖ;Canpolat U;Aras S;Celik O;Ata N;Birinci S;Çay S;Özeke Ö;Tanboğa IH;Topaloğlu S
通讯作者：
Topaloğlu S
DOI：
10.1016/s0140-6736(18)30668-8
发表时间：
2018-05-05
期刊：
Lancet (London, England)
影响因子：
--
作者：
Gilbert T;Neuburger J;Kraindler J;Keeble E;Smith P;Ariti C;Arora S;Street A;Parker S;Roberts HC;Bardsley M;Conroy S
通讯作者：
Conroy S
影响因子：
4.1
作者：
Rezaei-Shahsavarloo Z;Atashzadeh-Shoorideh F;Gobbens RJJ;Ebadi A;Ghaedamini Harouni G
通讯作者：
Ghaedamini Harouni G
DOI：
10.1093/gerona/56.3.m146
发表时间：
2001-03-01
影响因子：
5.1
作者：
Fried, LP;Tangen, CM;McBurnie, MA
通讯作者：
McBurnie, MA