Very low-frequency transcranial electrical stimulation over the primary motor area can influence the voluntary movement initiation in humans

Very low-frequency transcranial electrical stimulation over the primary motor area can influence the voluntary movement initiation in humans
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主运动区的极低频经颅电刺激可以影响人类的随意运动启动

DOI:
10.1016/j.brs.2023.01.1679
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发表时间:
2023
期刊:
影响因子:
7.7
通讯作者:
Mima Tatsuya
Mima Tatsuya
中科院分区:
医学1区
文献类型:
--
作者:
Shibata Sumiya;Watanabe Tatsunori;Otsuru Naofumi;Onishi Hideaki;Mima Tatsuya

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2.结果综合所有受试者(n=16),VS-Tacs和AM-Tacs的手指运动间隔分布呈右倾(图1B),这在以前的自愿行动研究中是常见的。VS-TAC组手指运动间隔为12.0±5.9秒,AM-TAC组为11.6±6.2秒。两组间差异无统计学意义(t检验,p=0.253)。卡方检验表明,在VS-TAC(图1C)中,运动起始的分布明显偏离均匀(p=0.027)。这一运动最常在π/2-π发起。在AM-TAC中,运动起始的分布没有明显偏离均匀度(p=0.620)。相对于肌电(EMG)起始点的平均VS-TAC在其前面显示一个逐渐上升的波形(图1D),这与MRCP的波形相似[1]。从肌电开始前的1.68秒开始,它明显偏离了95%的可信区间。讨论
2. ResultsWhen pooled across all participants (n= 16), the distribution of intervals between finger movements in both VS-tACS and AM-tACS showed a rightward skew (Fig. 1 B), which was commonly observed in previous voluntary action studies. The intervals between finger movements were 12.0±5.9 seconds in VS-tACS and 11.6±6.2 seconds in AM-tACS. They were not significantly different (t-test, p= 0.253). Chi-square test demonstrated that the distribution of movement initiation was significantly departed from uniformity (p= 0.027) in VS-tACS (Fig. 1 C). The movement was initiated most frequently in π/2–π. In AM-tACS, the distribution of movement initiation was not significantly departed from uniformity (p= 0.620). The averaged VS-tACS with respect to the electromyography (EMG) onset showed a gradually rising waveform preceding it (Fig. 1 D), which is similar to the waveform of MRCP [1]. It deviated significantly from the 95% CI approximately from 1.68 seconds prior to the EMG onset.3. Discussion
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