Influence of primary care physician availability and socioeconomic deprivation on breast cancer from 1988 to 2008: a spatio-temporal analysis.
Influence of primary care physician availability and socioeconomic deprivation on breast cancer from 1988 to 2008: a spatio-temporal analysis.
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DOI：
10.1371/journal.pone.0035737
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发表时间：
2012
期刊：
影响因子：
3.7
通讯作者：
Schootman M
中科院分区：
文献类型：
--
作者：
Chien LC;Deshpande AD;Jeffe DB;Schootman M
乳腺癌是美国女性最常见的确诊癌症，也是女性癌症死亡的第二大原因。目前尚不清楚县级初级保健医生(PCP)的可获得性和社会经济匮乏如何影响乳腺癌发病率和死亡率的时空变化。我们利用1988-2008年9个监测、流行病学和最终结果(SEER)项目的公共使用县数据，分析了五氯联苯可获得性和社会经济剥夺在早期发病率、晚期发病率和乳腺癌死亡率方面的时空差异。时空分析采用了一种新的结构加法建模方法。在整个研究期间，获得更多的五氯苯酚与较高的早期发病率、晚期发病率和死亡率显著相关，而直到1992年，社会经济剥夺与早期发病率、晚期发病率和死亡率显著负相关。然而，观察到的五氯酚有效性和社会经济剥夺的影响因县而异。我们显示了五氯苯酚的可获得性和社会经济匮乏与三项乳腺癌指标之间的重要关联。然而，这些协会的影响随着时间的推移和不同的县而有所不同。在选定的县中，五氯苯酚的有效性与社会经济贫困之间的关联性更强。
Breast cancer is the most commonly diagnosed cancer and the second leading cause of cancer death among women in the United States. It is unclear how county-level primary care physician (PCP) availability and socioeconomic deprivation affect the spatial and temporal variation of breast cancer incidence and mortality. We used the 1988–2008 public-use county-based data from nine Surveillance, Epidemiology, and End Results (SEER) programs to analyze the temporal and spatial disparity of PCP availability and socioeconomic deprivation on early-stage incidence, advanced-stage incidence and breast cancer mortality. The spatio-temporal analysis was implemented by a novel structural additive modeling approach. Greater PCP availability was significantly associated with higher early-stage incidence, advanced-stage incidence and mortality during the entire study period while socioeconomic deprivation was significantly negatively associated with early-stage incidence, advanced-stage incidence, and mortality up to 1992. However, the observed influence of PCP availability and socioeconomic deprivation varied by county. We showed important associations of PCP availability and socioeconomic deprivation with the three breast cancer indicators. However, the effect of these associations varied over time and across counties. The association of PCP availability and socioeconomic deprivation was stronger in selected counties.
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影响因子：
10.3
作者：
Glass, Andrew G.;Lacey, James V., Jr.;Hoover, Robert N.
通讯作者：
Hoover, Robert N.
DOI：
10.1111/1467-9876.00229
发表时间：
2001-01-01
影响因子：
1.6
作者：
Fahrmeir, L;Lang, S
通讯作者：
Lang, S
影响因子：
3.2
作者：
Lopez, Ellen D. S.;Khoury, Amal J.;Chisholm, Latarsha R.
通讯作者：
Chisholm, Latarsha R.
影响因子：
1
作者：
BESAG, J;YORK, J;MOLLIE, A
通讯作者：
MOLLIE, A
影响因子：
10.3
作者：
BallardBarbash, R;Potosky, AL;Kessler, LG
通讯作者：
Kessler, LG