Action of progesterone and RU38486 on protein synthesis in rat placenta.
Action of progesterone and RU38486 on protein synthesis in rat placenta.
复制标题
黄体酮和 RU38486 对大鼠胎盘蛋白质合成的作用。
DOI：
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发表时间：
1987
影响因子：
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通讯作者：
T. Mills
中科院分区：
文献类型：
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作者：
T. Ogle;T. Nosek;T. Mills
维持妊娠的预后作用包括抑制子宫肌层收缩和局部抑制母体免疫系统。除了这些作用外，这项研究还表明孕酮（P）还直接维持胎盘功能。我们认为，这种作用是由先前表征的胎盘核孕酮受体（Rpn）介导的（Ogle，1986 a，B）。本研究探讨了卵巢切除术（OVX）和抗孕酮，RU 38486（RU），对Rpn和蛋白质合成的调节的影响。在本报告中，蛋白质合成能力被用作胎盘功能的生理指标。
Progesterone action in maintenance of pregnancy includes inhibition of myometrial contractility and local suppression of the maternal immune system. In addition to these actions, this study indicates that progesterone (P) also directly maintains placental function. We propose that this action is mediated by the placental nuclear progesterone receptor (Rpn) characterized previously (Ogle, 1986a,b). This study examines the effects of ovariectomy (OVX) and the antiprogestin, RU38486 (RU), on the Rpn and on the regulation of protein synthesis. Capacity for protein synthesis is used in this report as a physiological indicator of placental function.
生物系统中蛋白质合成的测量。
影响因子：
6.1
作者：
Rannels,DE;Wartell,SA;Watkins,CA
通讯作者：
Watkins,CA