Effect of cognitive impairment on risk of death in Hispanic/Latino adults over the age of 50 residing in the United States with and without diabetes: Data from the Health and Retirement Study 1995-2014.
Effect of cognitive impairment on risk of death in Hispanic/Latino adults over the age of 50 residing in the United States with and without diabetes: Data from the Health and Retirement Study 1995-2014.
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DOI：
10.1002/alz.12521
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发表时间：
2022-09
期刊：
影响因子：
--
通讯作者：
中科院分区：
文献类型：
--
作者：
了解美国西班牙裔老年人有无糖尿病患者死亡率与认知功能之间的关系。分析了健康与退休研究（1995-2014）的数据。考克斯比例风险模型用于估计死亡率和认知功能之间的关联。模型按糖尿病分层。其中包括4，013名美国西班牙裔成年人。糖尿病患者的完全校正模型显示，与正常认知相比，轻度认知障碍（MCI）（HR：1.61; 95% CI：1.06，2.45; p=0.025）和痴呆（HR：2.14; 95% CI：1.25，3.67; p=0.006）患者的死亡率增加。针对无糖尿病个体的完全校正模型显示，与正常认知相比，MCI（HR：1.87; 95% CI：1.28，2.74; p=0.001）和痴呆（HR：3.25; 95% CI：1.91，5.55; p<0.001）患者的死亡率增加。认知功能障碍与美国西班牙裔老年人伴或不伴糖尿病的死亡率增加相关。临床医生应定期评估这一群体的认知功能，以快速识别衰退，并进行适当的转诊，以优化健康和降低死亡率。
Understand the relationship between mortality and cognitive function among older US Hispanic adults with and without diabetes. Data from the Health and Retirement Study (1995–2014) was analyzed. Cox proportional hazard models were used to estimate the association between mortality and cognitive function. Models were stratified by diabetes. 4,013 older US Hispanic adults were included. Fully adjusted models for individuals with diabetes showed those with mild cognitive impairment (MCI) (HR:1.61; 95% CI: 1.06, 2.45; p=0.025) and dementia (HR:2.14; 95% CI: 1.25, 3.67; p=0.006) had increased mortality compared to normal cognition. Fully adjusted models for individuals without diabetes, showed those with MCI (HR:1.87; 95% CI: 1.28, 2.74; p=0.001) and dementia (HR:3.25; 95% CI: 1.91, 5.55; p<0.001) had increased mortality compared to normal cognition. Cognitive impairment is associated with increased mortality in older US Hispanic adults with and without diabetes. Clinicians should regularly assess cognitive function in this group to quickly identify declines, and make appropriate referrals for support to optimize health and reduce mortality.
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DOI：
10.1016/j.trci.2018.08.009
发表时间：
2018
期刊：
Alzheimer's & dementia (New York, N. Y.)
影响因子：
--
作者：
Chen C;Zissimopoulos JM
通讯作者：
Zissimopoulos JM
影响因子：
8
作者：
Cortes-Bergoderi, Mery;Goel, Kashish;Lopez-Jimenez, Francisco
通讯作者：
Lopez-Jimenez, Francisco
影响因子：
2.1
作者：
Mayeda, Elizabeth R.;Haan, Mary N.;Neuhaus, John
通讯作者：
Neuhaus, John
影响因子：
3.9
作者：
Hu, Jie;Amirehsani, Karen A.;Silva, Zulema
通讯作者：
Silva, Zulema
影响因子：
3.9
作者：
Kolb, Leslie
通讯作者：
Kolb, Leslie