Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
Transcriptional Regulation of Aluminum-Tolerance Genes in Higher Plants: Clarifying the Underlying Molecular Mechanisms.
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DOI：
10.3389/fpls.2017.01358
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发表时间：
2017
影响因子：
5.6
通讯作者：
Koyama H
中科院分区：
文献类型：
--
作者：
Daspute AA;Sadhukhan A;Tokizawa M;Kobayashi Y;Panda SK;Koyama H
铝根毒害是导致全球粮食减产的主要环境胁迫之一。阐明耐铝的分子机制可能有助于耐铝作物的育种。最近的研究发现了多种耐铝基因。这些基因的表达是受铝诱导的。对拟南芥主要耐铝基因拟南芥铝激活的苹果酸转运蛋白1(AtALMT1)的研究表明，铝诱导的苹果酸转运蛋白的表达受一个对质子RHIXOTOXITY 1(STOP1)锌指转录因子敏感的调控。这个系统涉及STOP1和有机酸转运蛋白，在不同的植物物种中都是保守的。AtALMT1的表达也被几种植物激素和过氧化氢上调，这表明参与AtALMT1转录调控的信号之间存在串扰。此外，植物激素和活性氧物种(ROS)激活了各种转录反应，包括与铝胁迫条件下提高耐铝性或抑制根生长相关的基因表达。例如，由于生长素和细胞分裂素的异常积累，铝抑制了根的生长。它在远端过渡区激活拟南芥1号色氨酸转氨酶和其他植物激素反应基因的转录，从而抑制根的伸长。另一方面，谷胱甘肽-S-转移酶、过氧化物酶、超氧化物歧化酶等ROS解毒酶的铝诱导基因的过表达提高了几种植物的抗铝性。在此，我们综述了受STOP1、植物激素和ROS影响的铝诱导基因的复杂转录调控。
Aluminum (Al) rhizotoxicity is one of the major environmental stresses that decrease global food production. Clarifying the molecular mechanisms underlying Al tolerance may contribute to the breeding of Al-tolerant crops. Recent studies identified various Al-tolerance genes. The expression of these genes is inducible by Al. Studies of the major Arabidopsis thaliana Al-tolerance gene, ARABIDOPSIS THALIANA ALUMINUM-ACTIVATED MALATE TRANSPORTER 1 (AtALMT1), which encodes an Al-activated malate transporter, revealed that the Al-inducible expression is regulated by a SENSITIVE TO PROTON RHIXOTOXICITY 1 (STOP1) zinc-finger transcription factor. This system, which involves STOP1 and organic acid transporters, is conserved in diverse plant species. The expression of AtALMT1 is also upregulated by several phytohormones and hydrogen peroxide, suggesting there is crosstalk among the signals involved in the transcriptional regulation of AtALMT1. Additionally, phytohormones and reactive oxygen species (ROS) activate various transcriptional responses, including the expression of genes related to increased Al tolerance or the suppression of root growth under Al stress conditions. For example, Al suppressed root growth due to abnormal accumulation of auxin and cytokinin. It activates transcription of TRYPTOPHAN AMINOTRANSFERASE OF ARABIDOPSIS 1 and other phytohormone responsive genes in distal transition zone, which causes suppression of root elongation. On the other hand, overexpression of Al inducible genes for ROS-detoxifying enzymes such as GLUTATHIONE–S-TRANSFERASE, PEROXIDASE, SUPEROXIDE DISMUTASE enhances Al resistance in several plant species. We herein summarize the complex transcriptional regulation of an Al-inducible genes affected by STOP1, phytohormones, and ROS.
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影响因子：
64.8
作者：
Blilou, I;Xu, J;Scheres, B
通讯作者：
Scheres, B
影响因子：
5.6
作者：
Jung JK;McCouch S
通讯作者：
McCouch S
影响因子：
3.9
作者：
Devi, SR;Yamamoto, Y;Matsumoto, H
通讯作者：
Matsumoto, H
DOI：
10.1073/pnas.0700117104
发表时间：
2007-06-05
影响因子：
11.1
作者：
Iuchi, Satoshi;Koyama, Hiroyuki;Kobayashi, Masatomo
通讯作者：
Kobayashi, Masatomo
影响因子：
2.8
作者：
Inostroza-Blancheteau, Claudio;Rengel, Zed;Reyes-Diaz, Marjorie
通讯作者：
Reyes-Diaz, Marjorie