WeightedLD: The Application of Sequence Weights to Linkage Disequilibrium

WeightedLD: The Application of Sequence Weights to Linkage Disequilibrium
复制标题

WeightedLD:序列权重在连锁不平衡中的应用

DOI:
10.1101/2021.06.04.447093
复制
发表时间:
2021
期刊:
--
影响因子:
--
通讯作者:
Charles O
Charles O
中科院分区:
--
文献类型:
--
作者:
Charles O

文献摘要

参考文献

相似文献

Sequence-weighting methods are commonly employed to account for biases in sequence datasets. We use a weighting scheme which considers the observed distinctiveness of sequences and apply it to calculations of linkage disequilibrium. Each sequence now contributes a weighted score to linkage disequilibrium measurements of pairwise loci. We demonstrate that this reduces the effect of uneven sampling, as underrepresented groups of sequences will each contribute more individually than redundant, similar sequences.AvailabilitySource code for a python and rust implementation are freely available at under an MIT license at github.com/ojcharles/WeightedLD.Contactr.goldstein@ucl.ac.uk or oscar.charles.18@ucl.ac.uk
DOI: 10.1093/nar/gkx1095
发表时间: 2018-01-04
影响因子: 14.9
作者:
NCBI Resource Coordinators
通讯作者: NCBI Resource Coordinators
DOI: 10.1093/molbev/mst010
发表时间: 2013-04
影响因子: 10.7
作者:
Katoh K;Standley DM
通讯作者: Standley DM
DOI: 10.1371/journal.pone.0080754
发表时间: 2013
期刊: PloS one
影响因子: 3.7
作者:
Koch E;Ristroph M;Kirkpatrick M
通讯作者: Kirkpatrick M
DOI: 10.1093/nar/22.22.4673
发表时间: 1994-11-11
影响因子: 14.9
作者:
THOMPSON, JD;HIGGINS, DG;GIBSON, TJ
通讯作者: GIBSON, TJ
DOI: 10.1038/s41598-019-47832-y
发表时间: 2019-08-06
期刊: SCIENTIFIC REPORTS
影响因子: 4.6
作者:
Park, Leeyoung
通讯作者: Park, Leeyoung